(BERLIN) #Coronavirus Report: Germany’s national and regional leaders have agreed to bar unvaccinated people from much of public life in a bid to fend off a fourth wave of #COVID19 #AceHealthDesk report

#AceHealthReport – Dec.05: Outgoing Chancellor Angela Merkel described the far-reaching measures as an act of “national solidarity”………….Only those who have been vaccinated or recently recovered from Covid will be allowed in restaurants, cinemas, leisure facilities and many shops.

#CoronavirusNewsDesk Merkel says that #COVID19 restrictions have to be tightened on unvaccinated people in public life and only those vaccinated should be allowed in outdoor facilities and that vaccinations could be made mandatory by February, the chancellor added.

A man walks past a placard which indicates the so-called 2G rule (vaccinated or recovered from Covid-19) for the Christmas market in the city of Dortmund, western Germany on December 1, 2021.
So-called 2G policies will be enforced across the country

Seventy-nine cases of the new Omicron variant of Covid-19 have been reported in 15 European countries so far, according to the EU’s European Centre for Disease Prevention and Control.

Germany’s fourth wave of Covid is its most severe so far, with another 388 deaths recorded in the past 24 hours. 

There is also growing concern about the spread of the Omicron variant, which EU health officials warn is likely to cause over half of all Covid cases in the next few months.

Mrs Merkel said hospitals were stretched to the point of patients having to be moved to different areas for treatment. “The fourth wave must be broken and this has not yet been achieved.”

“Given the situation, I think it is appropriate to adopt compulsory vaccination,” she said, while making clear that this would have to be approved by parliament.

Her successor Olaf Scholz, who is expected to take over as chancellor next Wednesday, had already said he backed the move, which would come a few weeks later than a similar Austrian law. Berlin Mayor Michael Müller said the vast majority of Covid cases were down to unvaccinated people.

The new measures are not described as a lockdown on the unvaccinated, although outgoing Health Minister Jens Spahn spoke earlier of a “quasi lockdown”.

Some German states already operate so-called 2G policies, and these will now become nationwide – 2G stands for genesen (recovered in the past six months) or geimpft (vaccinated). 

Under the measures agreed by Germany’s 16 states and federal leaders:

  • Unvaccinated people will be limited to meetings with their own household and two other people
  • The 2G rule will be enforced at restaurants and cultural venues and non-essential shops
  • Clubs will shut in areas where 350 cases have been recorded per 100,000 people in the past seven days – the national rate is over 400
  • Up to 30 million vaccinations will be carried out by Christmas – first, second or boosters
  • Outdoor events, including Bundesliga football, will have limited crowds of 15,000 and 2G rules
  • Fireworks on New Year’s Eve will be banned

While vaccinations have been stepped up in Germany – with almost a million carried out on Wednesday alone – only 68.7% of the population has been vaccinated, a relatively low rate for Western Europe.

#AceHealthDesk report …………..Published: Dec.05: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#berlin, #germany, #health, #vaccinated-v-unvaccinated

(LONDON) GOVUK Press Release Statement Report: MHRA approves Xevudy (sotrovimab), a #COVID19 treatment found to cut hospitalisation and death by 79% #AceHealthDesk report

#AceHealthReport – Dec.03: Another #COVID19 treatment, Xevudy (sotrovimab), has today been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) after it was found to be safe and effective at reducing the risk of hospitalisation and death in people with mild to moderate COVID-19 infection who are at an increased risk of developing severe disease.

#CoronavirusNewsDesk says this monoclonal antibody – the second to be authorised by the Medicines and Healthcare products Regulatory Agency – is for people with mild to moderate #COVID19 who are at high risk of developing severe disease according to

This follows a rigorous review of its safety, quality and effectiveness by the UK regulator and the government’s independent expert scientific advisory body, the Commission on Human Medicines, making it the second monoclonal antibody therapeutic to be approved following Ronapreve.

Developed by GSK and Vir Biotechnology, sotrovimab is a single monoclonal antibody. The drug works by binding to the spike protein on the outside of the COVID-19 virus. This in turn prevents the virus from attaching to and entering human cells, so that it cannot replicate in the body.

In a clinical trial, a single dose of the monoclonal antibody was found to reduce the risk of hospitalisation and death by 79% in high-risk adults with symptomatic COVID-19 infection.

Based on the clinical trial data, sotrovimab is most effective when taken during the early stages of infection and so the MHRA recommends its use as soon as possible and within five days of symptom onset.

Like molnupiravir, it has been authorised for use in people who have mild to moderate COVID-19 infection and at least one risk factor for developing severe illness. Such risk factors include obesity, older age (>55 years), diabetes mellitus, or heart disease.

Unlike molnupiravir, sotrovimab is administered by intravenous infusion over 30 minutes. It is approved for individuals aged 12 and above who weigh more than 40kg.

It is too early to know whether the omicron variant has any impact on sotrovimab’s effectiveness but the MHRA will work with the company to establish this.

Dr June Raine, MHRA Chief Executive said:

“I am pleased to say that we now have another safe and effective COVID-19 treatment, Xevudy (sotrovimab), for those at risk of developing severe illness.

“This is yet another therapeutic that has been shown to be effective at protecting those most vulnerable to COVID-19, and signals another significant step forward in our fight against this devastating disease.

“With no compromises on quality, safety and effectiveness, the public can trust that the MHRA have conducted a robust and thorough assessment of all the available data.”

Professor Sir Munir Pirmohamed, Chair of the Commission on Human Medicines, said:

“The Commission on Human Medicines and its COVID-19 Therapeutics Expert Working Group has independently reviewed the data and agrees with the MHRA’s regulatory approval of Xevudy (sotrovimab).

“When administered in the early stages of infection, sotrovimab was found to be effective at reducing the risk of hospitalisation and death in high-risk individuals with symptomatic COVID-19. Based on the data reviewed by the Commission and its expert group, it is clear sotrovimab is another safe and effective treatment to help us in our fight against COVID-19.”

Sotrovimab is not intended to be used as a substitute for vaccination against COVID-19.

The government and the NHS will confirm how this COVID-19 treatment will be deployed to patients in due course.

Additional Notes:

  • The Medicines and Healthcare products Regulatory Agencyis responsible for protecting and improving the health of millions of people every day through the effective regulation of all medicines and medical devices in the UK by ensuring they work and are acceptably safe. All our work is underpinned by robust and fact-based judgements to ensure that the benefits justify any risks.
  • The MHRA is a centre of the Medicines and Healthcare products Regulatory Agency which also includes theNational Institute for Biological Standards and Control (NIBSC)and theClinical Practice Research Datalink (CPRD). MHRA is an executive agency of theDepartment of Health and Social Care.
  • TheCommission on Human Medicines (CHM) advises ministers on the safety, efficacy and quality of medicinal products. The CHM is an advisory non-departmental public body, sponsored by the Department of Health and Social Care.
  • The MHRA’s Conditional Marketing Authorisation for sotrovimab is valid in Great Britain only. An emergency use authorisation has been granted for Northern Ireland to ensure access across the whole of the United Kingdom. Both authorisations were made on the basis of the same rigorous evaluation.
  • More information can be found in the product information

#AceHealthDesk report …………..Published: Dec.03: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#govuk, #health, #london, #mhra

(LONDON) ONS REPORT: An estimated 1.2 million people living in private households in the UK (1.9% of the population) were experiencing self-reported long #COVID19 (symptoms persisting for more than four weeks #AceHealthDesk report

#AceHealthReport – Dec.03: ONS has just published the latest health data on ‘long covid’ that they now say 1.9% of the population are experiencing here is their latest press release …..

#AceDailyNews ONS Data Report: of people living in ‘private households’ experiencing self-reported long-covid19′ with symptoms lasting longer than 4-weeks….

1. Main points

  • An estimated 1.2 million people living in private households in the UK (1.9% of the population) were experiencing self-reported long COVID (symptoms persisting for more than four weeks after the first suspected coronavirus (COVID-19) infection that were not explained by something else) as of 31 October 2021; this is consistent with the 1.2 million (1.9%) seen as of 2 October 2021.
  • The estimates presented in this analysis relate to self-reported long COVID, as experienced by study participants who responded to a representative survey, rather than clinically diagnosed ongoing symptomatic COVID-19 or post-COVID-19 syndrome in the full population.
  • Of people with self-reported long COVID, 232,000 (19%) first had (or suspected they had) COVID-19 less than 12 weeks previously; 862,000 people (71%) first had (or suspected they had) COVID-19 at least 12 weeks previously, and 439,000 (36%) first had (or suspected they had) COVID-19 at least one year previously.
  • The proportion of people with self-reported long COVID who reported that it reduced their ability to carry out daily activities remained stable compared with previous months; symptoms adversely affected the day-to-day activities of 775,000 people (64% of those with self-reported long COVID), with 232,000 (19%) reporting that their ability to undertake their day-to-day activities had been “limited a lot”.
  • Fatigue continued to be the most common symptom reported as part of individuals’ experience of long COVID (54% of those with self-reported long COVID), followed by shortness of breath (36%), loss of smell (35%), and difficulty concentrating (28%).
  • As a proportion of the UK population, prevalence of self-reported long COVID remained greatest in people aged 35 to 69 years, females, people living in more deprived areas, those working in health or social care, and those with another activity-limiting health condition or disability.

If you are worried about new or ongoing symptoms four or more weeks after having COVID-19, there are resources available to help: see the NHS webpage on the long-term effects of coronavirus and the NHS Your COVID Recovery website, which can help you to understand what has happened and what you might expect as part of your recovery. The time it takes to recover from COVID-19 is different for everyone, and the length of your recovery is not necessarily related to the severity of your initial illness or whether you were in hospital.!

This is analysis of new, recently collected data, and our understanding of it and its quality will improve over time. Long COVID is an emerging phenomenon that is not yet fully understood. The estimates presented in this release are experimental statistics, which are series of statistics that are in the testing phase and not yet fully developed.Back to table of contents

This analysis was based on 341,882 responses to the Coronavirus (COVID-19) Infection Survey (CIS) collected over the four-week period ending 31 October 2021, weighted to represent people aged two years and over living in private households in the UK. Self-reported long COVID was defined as symptoms persisting for more than four weeks after the first suspected coronavirus infection that were not explained by something else. Parents and carers answered survey questions on behalf of children aged under 12 years.

Date of first (suspected) COVID-19 infection was taken to be the earliest of: date of first positive test for COVID-19 during study follow-up; date of first self-reported positive test for COVID-19 outside of study follow-up; date of first suspected coronavirus infection, as reported by the participant. Those with an unknown date of first (suspected) COVID-19 infection are in the estimates for “any duration” but not in duration specific estimates.

The definition of self-reported long COVID in this release is consistent with that used for “Approach 3” in our recently published technical articleon the prevalence of post-acute symptoms 4 or 12 weeks after COVID-19 infection. The estimates in this release are expressed out of everyone in the population; in contrast, the denominator for the estimates in our technical article is the number of infected people in the study sample. A further difference is that this analysis is based on confirmed and suspected COVID-19 infections, whereas the estimates in the technical article include only laboratory-confirmed cases.

The focus of this analysis is the population prevalence of self-reported long COVID. For data on the impact of long COVID, see results from the Opinions and Lifestyle Survey and the Schools Infection Survey.

The strengths and limitations of this analysis are described in a previous release. The survey questions relating to self-reported long COVID can be found in Section D of the CIS questionnaire. See Tables 2a to 2f of the technical datasets accompanying the latest Coronavirus (COVID-19) Infection Survey statistical bulletin for survey response rates.

#AceHealthDesk report ………..Published: Dec.03: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#coronavirusnewsdesk, #covid19, #health, #london, #ons

(BEIJING) #Coronavirus Report: China says it will deliver another 1 billion doses of #COVID19 vaccines to Africa and encourage Chinese companies to invest no less than $US10 billion ($14 billion) in the continent over the next three years #AceNewsDesk report

#AceHealthReport – Dec.01: In a speech via video link at the opening of the Forum on China-Africa Cooperation, Mr Xi said 600 million doses would be donations and 400 million doses would be provided through other means, such as joint production by Chinese companies and relevant African countries.

#CoronavirusNewsDesk says according to media news China’s Xi Jinping pledges another 1 billion #COVID19 vaccine doses for African nations: The country has already supplied nearly 200 million doses to Africa, where vaccination rates have fallen behind amid growing concern over the spread of the new Omicron variant of COVID-19, which was first identified in southern Africa.

Chinese President Xi Jinping is seated beside a Chinese flag as he addresses the United Nations General Assembly.
The vaccine diplomacy push comes as China’s Belt and Road Initiative, which finances major infrastructure in mainly developing nations, has slowed during the pandemic.(AP: UN Web TV)

“We must continue to fight together against COVID,” Mr Xi told the summit, adding that China would send about 1,500 medical workers to Africa.

“We must prioritise the protection of our people and close the vaccination gap.” 

Beijing has donated millions of doses of its home-produced Sinopharm vaccine to African countries since the start of the pandemic. 

China's Xi Jinping at Forum on China-Africa Cooperation
Beijing has promised to send about 1,500 medical workers to Africa in addition to the vaccine doses.(Reuters: Cooper Inveen)

Mr Xi said a China-Africa cross-border yuan centre would be set up to provide African financial institutions with a credit line of $US10 billion, without giving further details.

China will provide $US10 billion of trade finance to support African exports, create a zone for trade and economic cooperation and build a China-Africa industrial park, he said.

The announcement comes amid criticism of China’s infrastructure-for-commodities deals that some experts say saddle countries with unsustainable debt.

Democratic Republic of Congo is currently reviewing a $6 billion deal with Chinese investors over concerns that it is not sufficiently beneficial to Congo.

The Belt and Road Initiative — in which Chinese institutions finance major infrastructure in mainly developing nations — has slowed: Chinese bank financing for infrastructure projects in Africa fell from $US11 billion in 2017 to $US3.3 billion in 2020, according to a report by international law firm Baker McKenzie.

During a four-nation tour of the region last week, US Secretary of State Antony Blinken said that Washington was pushing for cleaner deals without unsustainable debts.African leaders slam bansSouth African President Cyril Ramaphosa is calling on countries to “immediately and urgently” reverse travel bans following the discovery of the new coronavirus variant Omicron.

China’s imports from Africa, one of its key sources of crude oil and minerals, will reach $US300 billion in the next three years, Mr Xi said, adding that the two sides would cooperate in areas such as health, digital innovation, trade promotion and green development.

South Africa’s President, Cyril Ramaphosa, also speaking via video link, thanked China for its support and said African economies should be able to manufacture COVID-19 vaccines.

Discussions at the World Trade Organization on a temporary TRIPS waiver to make COVID-19 vaccines and treatments available to allneeded to be finalised, he said, while criticising the travel curbs imposed on South Africa.

Travel bans have been imposed worldwide on people travelling from southern Africa after the World Health Organisation last week announced a new COVID-19 variant of concern, dubbed Omicron.

Lower vaccination rates linked to increased risk of variants emerging

A female nurse in protective clothing stands over a man sitting writing on a clipboard
Advisers to the World Health Organization held a special session Friday to flesh out information about a worrying new variant of the coronavirus that has emerged in South Africa, though its impact on COVID-19 vaccines may not be known for weeks.(AP: Denis Farrell)

For months now, experts have been warning of the risk that dangerous new variants pose for developing countries with lower vaccination rates.

More than a dozen nations across Africa and the Middle East, as well as Australia’s nearby neighbour Papua New Guinea, have vaccinated just 1 or 2 per cent of their populations.

The End COVID For All campaign, backed by leading health and charity groups, has called on the Australian government to prioritise sharing the vaccine to lower income countries to reduce the risk of variants emerging.

“More than 19 low-income countries have such low rates of vaccination, that on current rates they would not vaccinate 70 per cent of their populations until after 2030,” a report published by the group last month stated.

“Without rapid, widespread vaccination to slow mutation there is a significant risk that variants will not respond to existing vaccines or boosters.”

Wires/ABC

#AceHealthDesk report …………..Published: Dec.01: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#africa, #beijing, #china, #health, #vaccine

(GENEVA) WHO REPORT: The pharmaceutical giants have announced work to develop a vaccine that will prevent complications from a new dangerous strain of #coronavirus, #Omicron #AceHealthDesk report

#AceHealthReport – Nov.29: Pfizer & BioNTech is ready to adapt an existing vaccine from coronavirus to a new strain. The company is waiting for a large amount of laboratory test data no later than two weeks to confirm that the strain requires adjustments to the vaccine production technology.

#CoronavirusNewsDesk says Pfizer, AstraZeneca and Moderna develop vaccines against new dangerous #COVID19 strain “OMICRON” PCR test does not detect any of the genes of the new strain: This was reported by CNBC .

The Johnson & Johnson; and AstraZeneca is already conducting research at the sites of the first Omicron outbreaks.

Moderna said Friday that the combination of mutations in the new strain “has a significant potential risk of accelerating the weakening of natural and vaccine-induced immunity.”

The company explained that the only way to somehow protect themselves from the risks of “omicron” while there is a third booster dose of injection. The Moderna study will involve volunteers who have received the third dose of the vaccine.

WHO says a new strain of #coronavirus #Omicron and what is known

The new strain has a large number of mutations, some of which are of concern to the WHO. It was first reported by the World Health Organization in South Africa on November 24.

https://www.who.int/

Preliminary data collected by experts indicate an increased risk of re-infection with this option compared to others. The number of cases of this option is increasing in almost all provinces of South Africa.

PCR test does not detect any of the genes of the new strain.

Omicron may make vaccines less effective and more transmissible, according to the UK Health Agency.

#AceHealthDesk report ………….Published: Nov.29: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#geneva, #health, #vaccine, #who

(LONDON) Press Release Statement Report: The UK’s Health Secretary Sajid Javid & China’s Health Minister Ma Xiaowei concluded the virtual meeting of the UK-China Health Dialogue on 26th November 2021 #AceHealthDesk report

#AceHealthReport – Nov.28: The two sides recognised the contribution made by the UK-China Health Dialogue since its establishment in 2007 in promoting mutual understanding and trust between the UK and China. They agreed to strengthen exchanges and develop a joint health plan for collaboration in key areas.

#AceDailyNews GOVUK Joint Statement Report: UK-China Health Dialogue: Health and Social Care Secretary Sajid Javid and China’s Health Minister Ma Xiaowei agreed to develop joint health plan for collaboration according to

During this meeting, the two sides acknowledged the challenges both countries had faced in the context of the COVID-19 pandemic and looked ahead to cooperation in future domestic and global challenges and opportunities in the coming years.

Both sides recalled the 2020 UK-China Health Dialogue and agreed the good progress made over recent years. In particular: policy exchanges on the COVID-19 pandemic, global health collaboration, antimicrobial resistance, medicines regulations, and working together on health in Africa.

Both sides agreed to collaborate on knowledge exchange and implementing evidence based practices in providing high quality healthcare to their people in the context of the COVID-19 pandemic, emerging infectious diseases, ageing populations, and the growing burden of non-communicable diseases.

Both sides agreed to cooperate on global health security through the UK-China public health agencies, specifically on infectious disease control, emerging infectious diseases, emergency response and antimicrobial resistance, food safety risk surveillance and assessment.

Both sides noted the significance of supporting opportunities for sharing and learning from addressing COVID-19 and future pandemic preparedness such as scaling up support for global COVID-19 surveillance, genomic sequencing capacity, and variant assessment capabilities to ensure a global recovery from Covid-19.

Both sides agreed to cooperate on multilateral engagement in the health space and work together to strengthen the WHO, particularly with regard to pandemic preparedness and response. Both sides agree to cooperate across the wider multilateral landscape on international protocols and with international organisations, specifically supporting countries to comply with International Health Regulations and international standards across all hazards; and taking action on global health threats such as antimicrobial resistance and the health impacts of climate change. Both sides agreed on the importance of taking concrete measures to improve pandemic preparedness and response

Both sides agreed continuing to strengthen the dialogue and exchanges on policy and enhance collaboration, specifically on health care for ageing populations, and to continue dialogue on health development in Africa.

Both sides agreed to work together to enable vaccines, therapeutics and diagnostics to be rapidly developed, tested and deployed both in public health emergencies and for ongoing global health challenges, including through strengthening clinical trials infrastructure.

Both sides agree to work together on medical education and training.

The two sides acknowledged the contribution made over the last year in the challenging context of the COVID-19 pandemic in sustaining UK-China relations and undertook to build on the progress made at the 2021 UK-China Health Dialogue. Both sides agreed to review progress and renew a Memorandum of Understanding on Health Cooperation between The National Health Commission of China and UK Department of Health and Social Care at the next Health Dialogue in 2022.

Signed in Beijing and London on 26th Nov 2021 in duplicate, each written in Chinese and English, both texts being equally valid.

Sajid Javid, Secretary of State, Department of Health & Social Care of the United Kingdom of Great Britain and Northern Ireland

MA Xiaowei, Minister for Health, National Health Commission of the People’s Republic of China

#AceHealthDesk report …………Published: Nov.28: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#china, #dhsc, #health, #london

(LONDON) ONS REPORT: Impact of #coronavirus #COVID19) on international migration after numbers have fallen from 271,000 in 2020 to around 34,000 this year #AceHealthDesk report

#AceHealthReport – Nov.26: In 2020, the #coronavirus #COVID19 #pandemic impacted on people’s ability to migrate to other countries. Governments around the world introduced policies and restrictions in response to the pandemic; air travel to and from the UK dropped by 95% in the early months. As a result, UK immigration and emigration patterns were very different to past trends.

#CoronavirusNewsDesk says here is the ONS Health News Report: This bulletin focuses on long-term international migration. For consistency, we have continued to use the UN definition of a long-term migrant: a person who moves to a country other than that of his or her usual residence for at least a year…..

Development of migration statistics

However, we acknowledge that the UN definition has its limits when applied to the extremely unusual circumstances of 2020, when it was very difficult for people to make definite plans. People may have wished to migrate to or from the UK but found themselves prevented from doing so by border restrictions.

Since the pandemic there is increasing interest in who is resident in the country at any given point in time. In a society where people are increasingly mobile, the definitions we currently use are becoming less useful for some purposes. Therefore, we are exploring how we can use alternative definitions of international migration alongside the UN definition in future. In 2022, we will consult users on which definitions would best meet their needs.

Impact of Brexit on international migration

The UK left the EU on 31 January 2020 and was in a “transition period” until 31 December 2020. During the transition period, the UK continued to be part of the customs union and the single market, and people could migrate between the UK and the EU without needing a visa.

The extent and nature of the impact of Brexit upon people’s migration decisions during 2020 is currently unknown.

Overview of migration statistics transformation

Traditionally, the International Passenger Survey (IPS) was the main source for estimating international migration to and from the UK. However, we had long acknowledged that the IPS had been stretched beyond its original purpose and that we needed to consider all available sources to understand international migration.

In March 2020, the IPS was suspended because of the onset of the coronavirus (COVID-19) pandemic. In response, we have accelerated our work to transform how migration is measured and are moving towards producing administrative data-based migration estimates, supported by statistical modelling. While the IPS resumed operation in January 2021, the decision was taken and announced in the August 2020 Migration Statistics Quarterly Report (MSQR) that going forward we would continue to focus on developing methods for measuring international migration using administrative data and statistical modelling, given the limitations of the IPS.

This bulletin forms part of a suite of international migration releases:

The results of Census 2021 will also be published next year. These will help us further understand the quality of the Office for National Statistics’ (ONS’) published migration estimates.!

These are the latest official estimates of international migration. However, they are derived from statistical modelling, entail a level of uncertainty, and are therefore badged as experimental. Back to table of contents

8. Measuring the data

Modelling

The Office for National Statistics (ONS) is developing methods for estimating UK international migration for 2020 and beyond. We previously reported on our methods in the methodology working paper: Using statistical modelling to estimate UK international migration, published April 2021.

We continue to use a time series approach to model international migration during Quarter 3 (July to Sept) and Quarter 4 (Oct to Dec) 2020. Detail on our original assumptions and methods is available in Section 8 of the Methodology Working Paper.

Modelled estimates for Quarter 3 and Quarter 4 2020 are provisional and subject to revision, as our models develop, and more data becomes available. Estimates for March and Quarter 2 2020 in this statistical bulletin have been revised in the light of data updates since April 2021. 

As before, we used a Delphi approach to gather expert opinion on our model assumptions and modelled estimates. We invited experts to give their views on our assumptions and to provide any other evidence that we should consider in our models.

For non-EU migration the experts were in favour of our modelled approach for Quarter 3 and Quarter 4 and revisions to March and Quarter (Apr to June) 2 2020. For EU and British migration, in the absence of alternative timely data, we continue to model immigration and emigration using non-EU migration trends based on Home Office Exit Checks data. For EU we have incorporated an additional adjustment to the model using the ratio of EU and non-EU IPS data. For British we model immigration (repatriation) using non-EU departure data, and vice-versa.

For Quarter 2 2020 we applied a travel options adjustment to reflect the different travel behaviours of non-EU and EU migrants. This considered increased opportunities for EU migrants to come to the UK or return home than non-EU migrants, given the continued operation of cross-channel travel services when air travel was virtually halted from April 2020. We have implemented the experts’ suggestion to turn off this adjustment from July 2020, when the proportion of cross-Channel travel (rail and ferry) reduced as air travel resumed near normal proportions.

Data revisions

The figures published in this bulletin are based on experimental statistical modelling. We will continue to develop and update our models for international migration. We are currently exploring the use of Home Office data on European Economic Area (EEA) nationals and Department for Work and Pensions Registration and Population Interaction Database (RAPID) and other data sources. We aim to introduce RAPID data to improve modelled estimates of EU migration for provisional data covering 2021 Quarter 1 and Quarter 2 published by March 2022. At the same time, we anticipate revisions to 2020 Quarter 3 and Quarter 4 to account for this new data source. More information on our progress towards bringing together provisional modelled and observed estimates of migration using administrative data sources, and our future approach to revisions will be published in our statistical design article.Back to table of contents

#AceHealthDesk report …………Published: Nov.26: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#health, #london, #migrants, #ons, #united-nations

(LONDON) Press Release Statement Report: Six African countries added to ‘RED LIST’ to protect public health as UK designates new #COVID19 variant under investigation #AceHealthDesk report

#AceHealthReport – Nov.26: The government is taking decisive precautionary action against a new #COVID19 variant by introducing travel restrictions on arrivals from South Africa, Botswana, Lesotho, Eswatini, Zimbabwe and Namibia from midday tomorrow (Friday 26 November).

#CoronavirusNewsDesk GOVUK Travel Report: That a new precautionary travel restrictions are being introduced as from midday today as the UK Health Security Agency confirms a new variant under investigation according to news release from

  • From midday Friday 26 November, South Africa, Botswana, Lesotho, Eswatini, Zimbabwe and Namibia will be added to the UK’s travel red list
  • Passengers arriving from 4am Sunday in England will be required to book and pay for a government-approved hotel quarantine facility for 10 days
  • British nationals arriving from these six countries between midday Friday and 4am Sunday, and who have been in these countries within the last 10 days, must quarantine at home for 10 days and take NHS PCR tests on day 2 and day 8, even if they already have a lateral flow test booking
  • Direct flights from the 6 countries will be banned from midday Friday until hotel quarantine is up and running from 4am Sunday 28 November
  • Precautionary move follows designation of a new variant under investigation by the UK Health Security Agency (UKHSA)

It comes as Variant B.1.1.529 is declared a variant under investigation (VuI) by the UK Health Security Agency (UKHSA).

The variant includes a large number of spike protein mutations as well as mutations in other parts of the viral genome. These are potentially biologically significant mutations which may change the behaviour of the virus with regards to vaccines, treatments and transmissibility. More investigation is required.

No cases have been identified in the UK. We’re taking these precautionary measures to protect public health and the progress we’ve made so far through our successful vaccination programme.

From midday on Friday 26 November, non-UK and Irish residents who have been in these countries in the previous 10 days will be refused entry into England. This does not apply to those who have stayed airside and only transited through any of these countries while changing flights.

UK and Irish residents arriving between midday Friday 26 November and 4am Sunday 28 November from these six countries will be required to self-isolate at home for 10 days. They must take PCR tests on Day 2 and Day 8 post-arrival. These can be NHS PCR tests and passengers should take them even if they have already booked or taken their lateral flow test.

UK and Irish residents arriving from 4am Sunday must isolate in a government-approved facility for 10 days. During their stay, they will be required to take a coronavirus test on day 2 and day 8.

A temporary ban on commercial and private planes travelling from the six countries will also come into force at midday on Friday until 4am Sunday to reduce the risk of importing this new variant under investigation while hotel quarantine is stood up. This excludes cargo and freight without passengers.

The UK government thanks the government of South Africa for its surveillance of this variant and its transparency.

Meanwhile UKHSA continues to monitor the situation closely, in partnership with scientific and public health organisations across the world, and we will offer to work collaboratively with the 6 countries that have been currently placed on the UK red list to understand the virus and possible mitigations.

Secretary of State for Health and Social Care, Sajid Javid, said:

As part of our close surveillance of variants across the world, we have become aware of the spread of a new potentially concerning variant, which UKHSA has designated a variant under investigation.

We are taking precautionary action to protect public health and the progress of our vaccine rollout at a critical moment as we enter winter, and we are monitoring the situation closely.

I want to pay tribute to our world-leading scientists who are working constantly to keep our country safe, and I urge everyone to keep doing their bit by the getting the jab and following public health guidance.

Transport Secretary, Grant Shapps, said:

We’ve always maintained public safety is our number one priority, which is why we’ve kept in place measures which allow us to protect the UK from new variants.

We’re taking this early precautionary action now to protect the progress made across the country, and will continue to keep a close eye on the situation as we continue into the winter.

Dr Jenny Harries, UKHSA Chief Executive, said:

Scientists at UKHSA are in constant close collaboration with colleagues around the world to identify and assess variants as soon as they emerge. This is the most significant variant we have encountered to date and urgent research is underway to learn more about its transmissibility, severity and vaccine-susceptibility. The results of these investigations will determine what public health actions may limit the impact of B.1.1.529.

This is a clear reminder to everyone that this pandemic is not over, and we all have a responsibility to do what we can to limit transmission and reduce the infection rate and prevent the emergence of new variants. This means coming forward for vaccination as soon as possible and following public health advice. Wear a face covering in crowded places where it’s difficult to avoid coming into close contact with others, try to meet people in well-ventilated areas and seek a test immediately if you have symptoms.

The first genomes of this variant were uploaded to the international GISAID database on 22 November. Genomes have now been uploaded from South Africa, Botswana and Hong Kong but the extent of spread is not yet determined.

The government has been clear it will take decisive action if necessary to contain the virus and has taken the decision to add these destinations to the red list.

We continue to work with the hospitality sector to ensure it is ready to meet any increased demand – with hundreds of rooms on standby which can be made available to book as needed.

British nationals in these countries should check Foreign, Commonwealth and Development Office (FCDO) travel advice and follow local guidance. The FCDO will continue to offer tailored consular assistance to British nationals in country in need of support overseas on a 24/7 basis.

The UKHSA produces risk assessments of the spread of variants of concern or variants under investigation internationally. These risk assessments cover a range of factors for each country including assessment of surveillance and sequencing capability, available surveillance and genome sequencing data, evidence of in-country community transmission of COVID-19 variants, evidence of exportation of new variants to the UK or other countries and travel connectivity with the UK.

Background

  • British and Irish citizens, or those with residence rights, arriving to England from countries on the red list must book a managed quarantine hotel in advance. The quarantine package will include a managed quarantine hotel, quarantine transport and a travel test package for COVID-19 tests on day 2 and day 8 of quarantine. Read more about booking and staying in a quarantine hotel
  • Further information on international travel requirements can be found elsewhere on GOV.UK, including advice on transiting through red list countries.
  • Arrivals to the UK will need to meet the UK’s health and border requirements and comply with the relevant quarantine restrictions if coming from a red country or if not fully vaccinated. If you do not have the correct documentation ready to meet UK health and border requirements, you may delay yourself and others, be denied boarding, or face a fine.
  • Passengers arriving after 4am Sunday 28 November will be required to book a managed quarantine service (MQS) quarantine hotel. Bookings will open from midday Friday 26 November.

#AceHealthDesk report ………….Published: Nov.26: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#dhsc, #health, #london, #omicron, #travel

(LONDON) IPC REPORT: Pfizer’s CEO has described the company as “thrilled” and the boss of the International Paralympic Committee (IPC) has said he is “extremely grateful” about the donation of doses to the Beijing 2022 Winter Olympics #AceHealthDesk report

#AceHealthReport – Nov.22: Pfizer’s CEO has described the company as “thrilled” and the boss of the International Paralympic Committee (IPC) has said he is “extremely grateful” about the donation of doses to the Beijing 2022 Winter Olympics.

#CoronavirusNewsDesk – Thrilled’ Pfizer-BioNTech seals deal with grateful Olympic & Paralympic chiefs according to RT News Report:

21 Nov, 2021 11:25  / Updated 2 hours ago

‘Thrilled’ Pfizer-BioNTech seals deal with grateful Olympic & Paralympic chiefs

The International Olympic Committee (IOC) is working with national committees as part of a huge vaccine drive ahead of the showpiece in February.

An agreement with the Covid vaccine powerhouses is a key part of their strategy to help everyone traveling to the Games to become vaccinated.

Competitors who are not fully jabbed will face an arduous 21-day quarantine period after arriving in Beijing.

❌𝗕𝗥𝗘𝗔𝗞𝗜𝗡𝗚❌ Beijing offers Covid vaccine booster shots ahead of Winter Olympics: The Chinese capital has begun rolling out the shots to people participating, organising or working at the Games. VIA @breakingnewsie – @BHheadlines— BH HEADLINES© (@BHheadlines) October 22, 2021

“We are thrilled that our Covid-19 vaccine will again help as part of the efforts to support Olympic and Paralympic athletes and delegations,”Pfizer boss Albert Bourla responded, adding that it was “important to note” that the doses would be produced in addition to existing quotas.

“We hope they will enjoy a sense of global community while competing at the highest level.”

Ugur Sahin, the CEO and co-founder of BioNTech, said the group was “honored” to “support the safety” of the Games by contributing vaccines.

“The return of the Olympic and Paralympic Winter Games is an historic moment representing the global community and how we stand together,” he said.

“With more than two billion doses already delivered, our vaccine continues to help protect lives around the world and reconnect after these months when the virus has been separating us.”

Pfizer donates vaccines to …athletes to enable the Beijing Winter Olympics to go ahead. The pharma giant has made more than $35b in profit this year alone from its COVID vax while programs trying to distribute jabs to the poor have struggled to secure the vaccines they need. pic.twitter.com/lrWUtYecJJ— Latika M Bourke (@latikambourke) November 19, 2021

IPC President Andrew Parsons said that the entire Paralympic movement was “extremely grateful” to the IOC for securing the donations.

“This is another measure in our plan to stage safe Games for the athletes and all the participants and builds on our successful collaboration,” said IOC President Thomas Bach, adding his gratitude.

Pfizer-BioNTech has had a busy week after the US Food and Drug Administration deployed an emergency use authorization to approve its booster jab for adults on Friday.

‘Russian vaccines are acceptable’: Athletes who get Covid jab will be allowed not to quarantine at Winter Olympics, organizers say

READ MORE: ‘Russian vaccines are acceptable’: Athletes who get Covid jab will be allowed not to quarantine at Winter Olympics, organizers say

The authorization, which came two months later than president Joe Biden had wanted, arrived amid data showing that the efficacy of vaccines wanes over time.

According to the Centers for Disease Control and Prevention (CDC), the Pfizer-BioNTech vaccine is 95 percent effective at preventing infection from the virus in people who receive two doses and have no evidence of being previously infected.

The CDC recommends the treatment for anyone aged over five, adding that it has an efficacy of more than 90 percent in children.

Side effects are said to be more common after a second dose, and ‘rare cases’ of myocarditis and pericarditis have been reported in adolescents and young adults.

A data summary said that Covid vaccines will “continue to undergo the most intensive safety monitoring in US history.”

#AceHealthDesk report …………Published: Nov.22: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#beijing, #covid19, #health, #london

(AUSTRIA) #Coronavirus Report: Chancellor Alexander Schallenberg said Friday that the country will go into a national lockdown to contain a fourth wave of coronavirus cases #AceHealthDesk

#AceHealthReport – Nov.21: Schallenberg said the lockdown will start Monday and initially last for 10 days. Most stores will close, and cultural events will be canceled: He initially said all students would have to go back into homeschooling. Wolfgang Mueckstein, the country’s health minister, later said that schools would remain open for those who needed to go there but all parents were asked to keep their children at home if possible.

#CoronavirusNewsDesk says according to News Report: Austria to enter lockdown, that will initially last for 10 days and bring in mandatory vaccinations starting this Monday …..

People wearing face mask to protect against the coronavirus as they visits a Christmas market in Vienna, Austria, Wednesday, Nov. 17, 2021. The Austrian a nationwide lockdown for unvaccinated people is in place to combat rising coronavirus infections and deaths. (AP Photo/Michael Gruber)

Starting on Feb. 1, the country will also make vaccinations mandatory, public broadcaster ORF reported.

“We do not want a fifth wave,” Schallenberg said, according to ORF. “Not do we want a sixth or seventh wave.”

Austria had initially introduced a national lockdown only for the unvaccinated that started Monday but as virus cases continued to skyrocket the government said it had no choice but to extend it to everyone.

“This is very painful,” Schallenberg said.

A demonstrator holds a placard reading 'No to compulsory vaccination' during an anti-vaccination protest at the Ballhausplatz in Vienna, Austria, on November 14, 2021. (Photo by GEORG HOCHMUTH/APA/AFP via Getty Images)

The national lockdown will initially last for 10 days, then the effects will be assessed and if virus cases have not gone down sufficiently, it can be extended to a maximum of 20 days.

Austria, a country of 8.9 million, has one of the lowest vaccination rates in Western Europe. For the past seven days, the country reported more than 10,000 new infection cases daily. 

Hospitals have been overwhelmed with many new #COVID19 patients, and deaths have been rising again, too.

#AceHealthDesk report …………Published: Nov.21: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#austria, #health, #vaccine

(LONDON) GOVUK Press Release Vaccine Statement Report: UK hits 12 million #COVID19 top-ups in record breaking week @DHSC #AceHealthDesk report

#AceHealthReport – Nov.14: More than two million boosters have been given to people across the UK in the last week, as the vaccination programme continues to accelerate.

#CoronavirusNewsDesk reports that 12 million people in the UK have received a #COVID19 booster or third jab according to

  • In just seven days – more than 2.4 million booster jabs have been given across the UK – the best week in the programme so far
  • More milestones hit as 80% of over 12s now had two doses

In a record-breaking week, the UK has topped 12 million booster and third jabs given in total across the UK – with hundreds of thousands of people coming forward every day to get the vital protection offered by top-up jabs ahead of the colder months.

A total of 12,164,586 booster jabs have now been given, with 340,943 recorded yesterday in the UK.

According to the latest stats, in the 7 days leading up to November 11, almost 2.5 million new boosters or third doses have been reported in the UK, which is the highest weekly increase so far.

The latest figures come in a week of major milestones, with England reporting a total of 90 million first, second and third doses being administered on Thursday, and 80% of over 12s now having had two doses.

Health and Social Care Secretary Sajid Javid said:

Another excellent week of significant milestones for our vaccination programme as 12 million people have now played their part by coming forward for a top-up jab to give not only themselves, but their loved ones vital protection this winter.

We’ve made it easier than ever to get your booster this week by opening up appointments so people can pre-book a month in advance and I continue to urge all those eligible to get your jab as soon as possible.

For everyone who has not yet come forward for a first dose, second dose or booster – this is a national mission and it is not too late. Every jab builds our wall of defence across the country ahead of Christmas.

Following an update to the National Booking Service earlier this week, booking a booster jab has never been easier. Those eligible for a top-up vaccine – people over 50 and those most at risk of COVID-19 – can pre-book their jab five months after their second dose, making it easier and more convenient to boost their protection into winter.

People will still receive their vaccine six months after their second dose, but the change will speed up the vaccination programme by allowing people to receive a jab the day they become eligible, rather than waiting for a convenient appointment.

Vaccines give high levels of protection but immunity reduces over time, particularly for older adults and at-risk groups, so it is vital that vulnerable people come forward to get their COVID-19 booster vaccine to top-up their defences and protect themselves this winter.

The latest evidence from SAGE shows that protection against symptomatic disease falls from 65%, up to three months after the second dose, to 45% six months after the second dose for the Oxford/AstraZeneca vaccine, and from 90% to 65% for the Pfizer/BioNTech vaccine. Protection against hospitalisation falls from 95% to 75% for Oxford/AstraZeneca and 99% to 90% for Pfizer/BioNTech.

Although the vaccine effectiveness against severe disease remains high, a small change can generate a major shift in hospital admissions. For example, a change from 95% to 90% protection against hospitalisation would lead to doubling of admissions in those vaccinated.

The booster programme is designed to top up this waning immunity. Early results from Pfizer show that a booster following a primary schedule of the same vaccine restores protection back up to 95.6% against symptomatic infection.

Vaccines Minister Maggie Throup said:

It is wonderful to see the momentum of the phenomenal vaccine programme which is saving lives and reducing pressure on the NHS.

Getting your jab ahead of the winter months could be the most important thing you do as we all look forward to spending more time with our families and friends at Christmas.

I urge all those eligible to come forward to give yourself the vital protection of the life-saving vaccines.

COVID-19 booster vaccines have been delivered or booked in at every older adult care home in England where safe to do so, with almost nine in 10 care homes already visited.

People are also able to book by calling 119 and can get vaccinated at hundreds of walk-in sites across the country without an appointment. Those eligible can use the NHS online walk-in finder to locate the most convenient site.

Dr Emily Lawson, head of the NHS Vaccination Programme, said:

It is fantastic to see we have hit the 12 million mark for the number of booster jabs delivered in the UK, including more than 10 million administered by the NHS across England in under two months and this couldn’t have been done without the hard work of NHS staff and volunteers up and down the country.

As booster bookings continue to boom and with hundreds of thousands of people getting their vital top-up doses every single day, I would urge the millions being invited for their booster in the coming weeks to book in as soon as possible – it will provide you and your loved ones vital protection throughout the winter.

Last month, clinical guidance was updated to enable boosters to be given slightly earlier to those at highest risk, where this makes operational sense to do so. This includes care home residents who may have received their second doses at different times to be vaccinated in the same session, as long as it has been five months since their second dose. It may also help with other vulnerable groups, such as housebound patients, so that they can have their flu and COVID-19 vaccines at the same time.

Vaccine confidence is high with data from the Office for National Statistics showing nearly all (94%) of those aged 50 to 69 say they would be likely to get their COVID-19 booster if offered, with the figure rising to 98% for those over 70.

Flu is another winter virus that can be serious. To give people the best protection over winter, those eligible for a free flu vaccine should come forward and book an appointment at either their GP practice or their local pharmacy, or take it up when offered by their employer or other healthcare provider.

The government has launched a nationwide advertising campaign, encouraging people eligible to get their booster and flu jabs to protect themselves and their loved ones and help reduce pressures on the NHS. This includes outdoor billboards, broadcast and community radio and TV.

The offer of a first and second COVID-19 vaccine remains open to anyone who is eligible. Vaccines are available free of charge and from thousands of vaccine centres, GP practices and pharmacies. Around 98% of people live within 10 miles of a vaccination centre in England and vaccinations are taking place at sites including mosques, community centres and football stadiums.

There are more than 500 extra vaccination sites now compared to April this year, with 1,697 vaccination centres in operation in April 2021, and over 2,200 vaccination centres in operation now.

Vaccines are also available for those aged 12-15 to offer the best possible protection this winter in schools, as well as more than 200 vaccine centres.

#AceNewsDesk report ………..Published: Nov.14: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#govuk, #health, #london, #vaccine

(LONDON) MHRA Press Release Statement Report: First oral antiviral for #COVID19, Lagevrio (molnupiravir), approved in tablet form #AceHealthDesk report

#AceHealthReport – Nov.04: The antiviral Lagevrio (molnupiravir) is safe and effective at reducing the risk of hospitalisation and death in people with mild to moderate #COVID19 who are at increased risk of developing severe disease, the Medicines and Healthcare products Regulatory Agency (MHRA) announced today.

#CoronavirusNewsDesk reports that MHRA The antiviral was found to be safe and effective following a stringent review of the available evidence……

This follows a rigorous review of its safety, quality and effectiveness by the UK regulator and the government’s independent expert scientific advisory body, the Commission on Human Medicines, making it the first oral antiviral for the treatment of COVID-19 to be approved.

Developed by Ridgeback Biotherapeutics and Merck Sharp & Dohme (MSD), Lagevrio works by interfering with the virus’ replication. This prevents it from multiplying, keeping virus levels low in the body and therefore reducing the severity of the disease.

Based on the clinical trial data, Lagevrio is most effective when taken during the early stages of infection and so the MHRA recommends its use as soon as possible following a positive COVID-19 test and within five days of symptoms onset

Molnupiravir has been authorised for use in people who have mild to moderate COVID-19 and at least one risk factor for developing severe illness. Such risk factors include obesity, older age (>60 years), diabetes mellitus, or heart disease.

Health and Social Care Secretary Sajid Javid said:

“Today is a historic day for our country, as the UK is now the first country in the world to approve an antiviral that can be taken at home for COVID-19. This will be a gamechanger for the most vulnerable and the immunosuppressed, who will soon be able to receive the ground-breaking treatment.

“The UK is leading the way to research, develop and roll out the most exciting, cutting-edge treatments, and my thanks goes to the expert teams at the MHRA and MSD for this triumph, as well as the Antivirals Taskforce who have procured the treatment.

“We are working at pace across the government and with the NHS to set out plans to deploy molnupiravir to patients through a national study as soon as possible

“This antiviral will be an excellent addition to our armoury against COVID-19, and it remains vital everyone comes forward for their life-saving COVID-19 vaccine – particularly those eligible for a booster – to ensure as many people as possible are protected over the coming months.”

Dr June Raine, MHRA Chief Executive, said:

“Following a rigorous review of the data by our expert scientists and clinicians, we are satisfied that Lagevrio (molnupiravir) is safe and effective for those at risk of developing severe COVID-19 disease and have granted its approval.

“Lagevrio is another therapeutic to add to our armoury against COVID-19. It is also the world’s first approved antiviral for this disease that can be taken by mouth rather than administered intravenously. This is important, because it means it can be administered outside of a hospital setting, before COVID-19 has progressed to a severe stage.

“With no compromises on quality, safety and effectiveness, the public can trust that the MHRA has conducted a robust and thorough assessment of the data.”

Professor Sir Munir Pirmohamed, Chair of the Commission on Human Medicines, said:

“The Commission on Human Medicines and its COVID-19 Therapeutics Expert Working Group has independently reviewed the data and endorses the MHRA’s regulatory approval of Lagevrio.

“In clinical trials, Lagevrio was found to be effective in reducing the risk of hospitalisation or death for at-risk non-hospitalised adults with mild to moderate COVID-19 by 50%.

“Based on this and other data that has been carefully reviewed by the Commission and its expert group, it is clear Lagevrio is another safe and effective treatment to help us in our fight against COVID-19.”

Lagevrio is not intended to be used as a substitute for vaccination against COVID-19.

The government and the NHS will confirm how this COVID-19 treatment will be deployed to patients in due course.

Additional Health Notes:

  • The Medicines and Healthcare products Regulatory Agencyis responsible for protecting and improving the health of millions of people every day through the effective regulation of all medicines and medical devices in the UK by ensuring they work and are acceptably safe. All our work is underpinned by robust and fact-based judgements to ensure that the benefits justify any risks.
  • The MHRA is a centre of the Medicines and Healthcare products Regulatory Agency which also includes theNational Institute for Biological Standards and Control (NIBSC)and theClinical Practice Research Datalink (CPRD). MHRA is an executive agency of theDepartment of Health and Social Care.
  • TheCommission on Human Medicines (CHM) advises ministers on the safety, efficacy and quality of medicinal products. The CHM is an advisory non-departmental public body, sponsored by the Department of Health and Social Care.
  • The MHRA’s Conditional Marketing Authorisation for Lagevrio is valid in Great Britain only. An emergency use authorisation has been granted for Northern Ireland to ensure access across the whole of the United Kingdom. Both authorisations were made on the basis of the same rigorous evaluation.

#AceHealthDesk report ……………Published: Nov.04: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#health, #london, #mhra

(LONDON) Press Release Statement Report: Clinical guidance has been updated to allow #COVID19 boosters to be given earlier to those at highest risk where this makes operational sense #AceHealthDesk report

#AceHealthReport – Oct.30: #COVID19 booster vaccines can now be given sooner than six months after their second dose to certain vulnerable people where this makes operational sense,

#CoronavirusNewsDesk reports on GOVUK as the UKHSA’s Green Book has been updated to allow flexibility in booster programme for most vulnerable according to DHSC report …

  • Flexibility means programme will protect the most vulnerable more quickly
  • Guidance clarification comes as the UK hits seven million boosters administered

It will for example allow care home residents who may have received their second doses at different times to be vaccinated in the same session, as long as it’s been five months since their second dose. It may also help with other vulnerable groups, such as housebound patients, so that they can have their flu and COVID-19 vaccines at the same time.

The flexibility in clinical guidance will speed up the administration of life-saving booster jabs, making it more efficient to reach the country’s most vulnerable, helping to ensure they’re protected over the coming winter months.

Also under this guidance, people who are eligible for a booster and are about to receive immunosuppressive treatment which would hinder their immune system will be able to get their booster from a minimum of four months after their second dose. This will ensure they can time their booster for when their immune system is best able to respond.

This is the practical approach to vaccination that has made the programme successful so far.

Health and Social Care Secretary Sajid Javid said:

We are making great progress with the booster rollout and I want to thank everyone working so hard to get jabs in arms.

This updated guidance will ensure healthcare professionals have the necessary flexibility in the booster programme, allowing more vulnerable people to be vaccinated where it makes operational sense to do so – including our loved ones in care homes.

The UKHSA’s Green Book contains the latest information on vaccines and vaccination procedures in the UK for healthcare professionals.

Those the guidance applies to will not need to take additional steps.

People outside of these specific circumstances will continue to be invited for the COVID-19 booster jab when it’s their turn, six months after their second dose – if they have not been contacted within a week of reaching six months since their second jab they can head online via NHS.UK to book their jab. People who cannot go online can call 119 too.

The independent Joint Committee on Vaccination and Immunisation (JCVI) has advised that those most at risk to the virus receive their booster six months after their second dose, based on the available evidence. The government accepted this advice earlier this year. This advice has not changed and the JCVI keeps its advice under continuous review, using the latest data available.

Vaccines give high levels of protection but immunity reduces over time, particularly for older adults and at-risk groups, so it is vital that vulnerable people come forward to get their COVID-19 booster vaccine to top-up their defences and protect themselves this winter.

The latest evidence from SAGE shows that protection against symptomatic disease falls from 65%, up to 3 months after the second dose, to 45% six months after the second dose for the Oxford/AstraZeneca vaccine, and from 90% to 65% for the Pfizer/BioNTech vaccine. Protection against hospitalisation falls from 95% to 75% for Oxford/AstraZeneca and 99% to 90% for Pfizer/BioNTech.

Although the vaccine efficacy against severe disease remains high, it should be noted that a small change can generate a major shift in hospital admissions (e.g. a change from 95% to 90% against hospitalisation would lead to doubling of admissions in those vaccinated).

The booster programme is designed to top up this waning immunity. Early results from Pfizer show that a booster following a primary schedule of the same vaccine restores protection back up to 95.6% against symptomatic infection.

The news comes as the UK hits over seven million booster jabs, after a record breaking week of more than two million being administered in the last seven days alone.

A total of 7,293,638 people have received their booster jab in the UK. 45,651,222 people have received two doses (79.4%) and 49,882,904 people have received one dose (86.7%).

Vaccines Minister Maggie Throup said:

COVID-19 booster vaccinations are extremely important in keeping people and their loved ones safe this winter, and this updated guidance will ensure the programme can adapt to best protect certain groups.

I encourage everyone eligible for their jab to book theirs as soon as possible and secure this protection.

Vaccine confidence is high with data from the Office for National Statistics showing nearly all (94%) of those aged 50 to 69 say they would be likely to get their COVID-19 booster if offered, with the figure rising to 98% for those over 70.

Flu is another winter virus. To give people the best protection over winter, those eligible for a free flu vaccine should come forward and book an appointment at either their GP practice or their local pharmacy, or take it up when offered by their employer or other healthcare provider.

There are more than 500 extra vaccination sites now compared to April this year, with 1,697 vaccination centres in operation in April 2021, and over 2,200 vaccination centres in operation now.

Vaccines are also available for those aged 12-15 to offer the best possible protection this winter in schools, as well as over 100 vaccine centres.

#AceHealthDesk report …………Published: Oct.30: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#govuk, #health, #london

(ENGLAND) Home Care Report: Many councils are not paying companies a high enough hourly rate to cover basic costs like travel time between clients, it says #AceHealthDesk report

#AceNewsReport – Oct.26: Low wages and feeling undervalued are key factors leading care staff to quit, says the report: Councils say they do not have enough money to pay companies more.

#AceDailyNews says according to a report Homecare costs outstrip funding from councils, they say and it means, despite losing staff faster than they can be replaced, companies are unable to raise wages, says the Homecare Association.

By Alison Holt and Judith Burns
BBC News

Care worker with elderly woman

The Homecare Association, which represents some 2,340 care providers, calculates the true minimum cost of providing an hour of homecare in the UK is £21.43.

This covers the minimum wage, travel time, pensions, holidays, training, PPE, office staff and 60p for profit or reinvestment in services. 

Private clients who hire care direct from providers pay an average £24.94 for an hour of homecare, according to separate analysis by software company The Access Group.

But private clients are a minority, with the bulk of homecare (about 70%) funded by the state, says the Homecare Association. 

Inequality

Freedom of Information data collected for the Association shows the average paid by councils in Great Britain and health boards in Northern Ireland is £18.45.

The report found that areas with some of the highest levels of deprivation also had the lowest average fee rates for homecare.

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The Homecare Association says with some local authorities still buying homecare by the minute, and little or no funding for better pay, it makes it very difficult to compete with other sectors for staff. 

Richard Walker, chief executive of Optimo Care Group in South Yorkshire, has tried to improve pay and conditions for staff, but says his efforts are limited by local authority funding levels. 

“We’re simply not competing… so I think people go elsewhere…

“It feels like we’re in a harder position now than we’ve ever been before.” 

Richard estimates that, overall, Optimo’s costs outstrip council funding by about 25%, although this varies according to local authority.

“We’re miles away at the moment in terms of the rates that have been paid.” 

The staff shortage means the company is having to turn away referrals – and he finds not being able to give people the help they require when they need it “really tough… quite demotivating”.Pay is not “level with the job you do out there”, says Denise Wickson

Among his staff is Denise Wickson, a home carer for 16 years. 

For Denise, the work brings “great reward, great satisfaction”.

“I love the job,” she says. 

But sometimes she can be up at 05:00 and not finish until 23:00. 

“You never get to switch off, you’re always worried, ‘Is it covered?’. You get called and they say you’re needed to go out. I never say no.” 

Denise says the money is not “level with the job you do out there”, and some people “just go elsewhere where it’s more money and it’s not unsociable hours”. 

‘Crisis point’

The Homecare Association says lack of support in the community can lead to:

  • hospitals unable to discharge patients who are medically ready
  • emergency admissions of people whose conditions deteriorate through lack of appropriate care

“It makes little sense to neglect people at home in the community, wait until they reach crisis point, then admit them to the most expensive setting of care in an acute hospital,” says the report. 

The Association wants central government to “invest properly” in homecare, raising pay to £11.20 per hour, at a cost of £1.6bn a year across the UK, plus:

  • a ban on purchasing homecare by the minute
  • a professional register for care workers
  • social care workers added to the Shortage Occupation List to make it easier to hire from overseas

The Association of Directors of Adult Social Services (ADASS) said: “Councils may want to pay more for care, but their hands are tied, because they simply do not have the money to do so.”

An ADASS spokesperson urged ministers to use Wednesday’s Spending Review to invest in care and support at home to “lift the pressure on family carers, ensure the viability of high quality home care providers, and properly reward the committed, courageous and compassionate people working in social care”.

The Local Government Association (LGA), which represents councils in England, said: “Councils work closely with care providers, and understand their concerns about paying a fair price for the cost of care. 

“Such is the scale of funding pressures, this is proving harder to achieve and we urgently need new national funding to meet immediate pressures in the social care system.” 

The government says a new £162.5m fund will help “bolster” the homecare workforce, while the social care levy, announced last month, includes £5.4bn earmarked for social care over the next three years, with £500m to be spent on the workforce.

But the LGA questions whether the levy will raise enough money to fund crucial reforms, and wants to see a greater share of it go to front-line social care.

#AceHealthDesk report …………….Published: Oct.26: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#care, #england, #health, #homecare, #travel, #u-k, #wages

(SCOTLAND) #Coronavirus Report: More than 500 cases of #COVID19 have been linked to the TRNSMT music festival, new data shows when 50,000 people mixed together #AceHealthDesk report

#AceHealthReport – Oct.10: Public Health Scotland said 551 who tested positive for the virus reported having been at the festival around the time of their illness when speaking to contact tracers.

#CoronavirusNewsDesk says according to BBC Health #COVID19 in Scotland have linked more than 500 cases to TRNSMT Music Festival with some 1,645 people who were also found to have been close contacts of those who tested positive when about 50,000 people descended on Glasgow Green for the three-day event last month but see the figures below from Saturday …..

TRNSMT crowd
PA Media: Up to 50,000 people descended on Glasgow Green for TRNSMT last month

They had to bring proof of a negative lateral flow test to gain entry. 

Public health expert Prof Linda Bauld said it was likely that some of these people were infected at TRNSMT but it was not a “super-spreader” event. 

The figures were published in response to a freedom of information request from the Press Association news agency. 

TRNSMT was one of the first mass events held in Scotland since the start of the pandemic. 

According to Public Health Scotland, the figures do not mean Covid-19 was contracted at the event, only that those who spoke to Test and Protect recorded having been at TRNSMT around the time of their illness.

Following the event which started on 10 September, national clinical director Professor Jason Leitch said the festival was not responsible for a spike in cases.

Prof Bauld, professor public health at the University of Edinburgh, said it was not possible to say definitely how people caught the virus at the festival. 

“I think it’s certainly possible that some of those cases were infected at TRNSMT but we can’t prove it,” she added. 

Decline in cases

Prof Bauld said there were always risks when mass events are held during periods of relatively high levels of infection in the community. 

At the time of TRNSMT about one in 60 people in Scotland had Covid. 

Be she added: “TRNSMT was not a super-spreader event. 

“It’s really important to recognise that in the weeks following the festival, we actually saw a decline in cases in Scotland and we certainly didn’t see a surge related to that festival. 

“But clearly it’s not without risk and that may be reflected in these numbers.”

In the week immediately following the festival, 30,928 cases of Covid-19 were recorded as part of the Scottish government’s daily tally, meaning the number of confirmed cases linked to TRNSMT was 1.7% of the total.

Weekly Covid cases in Scotland hit a peak of just under 44,900 in the week ending 6 September – just before TRNSMT. They have since fallen to just under 17,600 in the week to 3 October.

There were 2,627 cases recorded by the Scottish government on Friday and 16 deaths following a positive test.

#AceHealthDesk report…………………….Published: Oct.10: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#health, #scotland

(GERMANY) #Coronavirus Trial Report: BioNTech has said that vaccine is safe for children of 5 – 11yrs-of -age #AceHealthDesk report

#AceHealthReport – Sept.21: In participants five to 11 years of age, the vaccine was safe, well tolerated and showed robust neutralizing antibody responses,” Germany-based BioNTech and US pharma giant Pfizer said in a joint statement.

#CoronavirusNewsDesk says BioNTech has said their vaccines safe for kids 5 to 11 and Pharmaceutical companies BioNTech and Pfizer said Monday that their jointly produced coronavirus vaccine is safe and effective for chilldren from the ages of 5 to 11.

A health professional prepares a dose of BionNTech-Pfizer vaccine

The announcement comes as coronavirus cases among children surge in the United States and other parts of the world.

What did the companies say?

The two firms are going to hand over trial data to regulatory bodies in the EU, US and other parts of the world “as soon as possible.” Over 2,200 children took part in the trial. 

The children in the vaccine trial received two doses of 10 micrograms, spaced 21 days apart. Older age groups typically receive two shots of 30 micrograms. 

The smaller dosage meant the children experienced fewer side effects, such as sore arms or achiness, than older age groups.

Hoping for a normal year at school 

Coronavirus cases surge among children in US, other countries  

The statement comes as coronavirus cases among children surge in the United States and in other parts of the world.    

“We are eager to extend the protection afforded by the vaccine to this younger population,” Pfizer CEO Albert Bourla said, while adding that “since July, pediatric cases of COVID-19 have risen about 240 percent in the US.” 

The US Food and Drug Administration (FDA) has already approved BioNTech-Pfizer vaccine for children as young as 12. Other vaccine makers, such as Moderna and Johnson & Johnson, are also testing their jabs on younger children.  

The vaccine could greatly faciliate the safe return of school children to in-person classes in the US, UK and in other countries. Many Western nations have been reluctant to give jabs to children due to the lack of available data on safety and efficacy. 

COVID-19: Cuba vaccinates children as young as 2 

Israel has already greenlit vaccinations for children aged 5-11 who are at risk of serious illness from the virus. Cuba has vaccinated children as young as two-years-old to reopen schools.   

Although data may show the vaccine is effective and safe for children, some parents may still be reluctant or hesitant for their kids to receive the jab. This reluctance could pose a major challenge for inoculation campaigns in the US and elsewhere. 

wd/rt (AP, AFP)

#AceHealthDesk report ……Published: Sept.21: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#biontech, #children, #covid19, #germany, #health, #pfizer

(LONDON) PHE Statement Report: Latest list of confirmed case of #COVID19 cases variants identified in U.K. #AceHealthDesk report

#AceHealthReport – Sept.18: PHE releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

#CoronavirusNewsDesk reports on PHE confirmed cases of #COVID19 variants identified in UK from Wed.23: Dec: 2020: – Thurs.02: Sept: 2021: PHE: weekly updates

Latest updates on SARS-CoV-2 variants detected in UK.

Latest update:

Public Health England (PHE) has published variant technical briefing 23.

Previous

Thursday 2 September

Public Health England (PHE) has published variant technical briefing 22.

PHE releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

Friday 20 August

Public Health England (PHE) has published variant technical briefing 21.

PHE releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

Friday 6 August

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

PHE has today published the latest variant technical briefing. It shows that Delta is still overwhelmingly dominant across the UK, accounting for approximately 99% of cases. The briefing includes updated hospitalisation data for Delta, which shows that in the period since the last update on 19 July, 1,467 people were hospitalised with cases of Delta confirmed by sequencing or genotyping. Of these, 808 (55.1%) were unvaccinated, while 512 (34.9%) had received both doses of the vaccine. While vaccines provide high levels of protection, they are not 100% effective and will not stop everyone catching COVID-19. As more of the population gets vaccinated, we will see a higher relative percentage of vaccinated people in hospital.

The Technical Briefing also includes some initial findings which indicate that levels of virus in those who become infected with Delta but have already been vaccinated may be similar to levels found in unvaccinated people. This may have implications for people’s infectiousness, whether they have been vaccinated or not. However, this is early exploratory analysis and further targeted studies are needed to confirm whether this is the case.

PHE has also published the risk assessment on VUI-21JUL-01, also known as B.1.621. VUI-21JUL-01 was designated a variant under investigation (VUI) on 21 July, based on apparent spread into multiple countries, as well as importation to the UK and mutations of concern, which include E484K, N501Y and K417N. These mutations have also been detected in other variants under investigation (VUIs) and variants of concern (VOCs). As of 4 August 2021, there were 37 confirmed VUI-21JUL-01 cases in England. Cases have been detected across 6 English regions, with most cases in London. Cases have also been reported in several other countries.

There is preliminary laboratory evidence to suggest that vaccination and previous infection may be less effective at preventing infection with VUI-21JUL-01. However, this data is very limited and more research is required. There is no evidence to suggest that VUI-21JUL-01 is more transmissible than the dominant Delta variant.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency, said:

The latest hospitalisation figures show once again how important it is that we all come forward to receive both doses of the vaccine as soon as we are able to do so. Vaccination is the best tool we have in keeping ourselves and our loved ones safe from the serious disease risk COVID-19 can pose.

However, we must also remember that the vaccines do not eliminate all risk: it is still possible to become unwell with COVID-19 and infect others. It is still vital that we exercise caution, particularly while cases are high. Remember that meeting outdoors is safer than indoors, isolate if you are told to by NHS Test and Trace, and if you show symptoms stay home and get a PCR test as soon as possible. It is so important that we all continue to play our part.

Friday 23 July

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

PHE’s weekly COVID-19 variant cases data shows that numbers of confirmed cases of the Delta (VOC-21APR-02) variant in the UK have risen by 33,716 since last week to a total of 286,765. Of these, 45 are the Delta AY.1 sub lineage. The Delta variant currently accounts for approximately 99% of cases across the UK.

PHE has also published the latest edition of the variant technical briefing. This includes updated hospitalisation data showing that between 21 June and 19 July, 1,788 people were admitted to hospital after testing positive for the delta variant. Of these, 970 (54.3%) were unvaccinated, while 530 (29.6%) had received both doses of the vaccine. In total, 3,692 people have been hospitalised with the Delta variant, of whom 2,152 (58.3%) were unvaccinated and 843 (22.8%) were fully vaccinated.

PHE has also published updated risk assessments for the Delta and Beta variants. The Delta risk assessment has been updated to reflect early signs of increased risk of reinfection with Delta compared to Alpha. Further investigations are being undertaken.

New variant under investigation

A further variant, B.1.621, was designated a variant under investigation (VUI) on 21 July 2021, having previously been designated a signal in monitoring. The new designation was made on the basis of early analysis of its genetic profile as well as its apparent international expansion and subsequent importation to the UK.

Sixteen confirmed cases of B.1.621 have been identified across the country to date, and the majority have been linked to overseas travel. There is currently no evidence of community transmission in the UK.

There is currently no evidence that this variant causes more severe disease or renders the vaccines currently deployed any less effective. PHE is carrying out laboratory testing to better understand the impact of mutations on the behaviour of the virus.

All appropriate public health interventions will be undertaken, including additional contact tracing and targeted testing. Where cases have been identified, additional follow-up of cases, testing of contacts and if required targeted case finding will be deployed to limit its spread.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency, said:

This most recent hospitalisation data shows once again just how crucial vaccination is in protecting us from severe illness and death. Two doses of vaccine are far more effective against COVID-19 than a single dose, so please make sure that you come forward to get your second dose as soon as you are invited.

As we emerge from restrictions and vaccine coverage continues to rise, it is important to remember that while the protection provided by vaccination is excellent, it is not total. It is still as important as ever that we continue to exercise caution. Remember that meeting outside is safer than inside, get 2 doses of the vaccine as soon as you can, isolate if you are told to by NHS Test and Trace and if you show symptoms stay home and get a PCR test. COVID-19 has not gone away and we must all continue to play our part.

Friday 16 July

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

PHE’s weekly COVID-19 variant cases data shows that numbers of the Delta (VOC-21APR-02) variant in the UK have risen by 36,800 since last week to a total of 253,049. This represents a 17% increase. Of these, 45 are the Delta AY.1 sub lineage. The Delta variant currently accounts for approximately 99% of cases that are sequenced across the UK.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency, said:

Case rates are still high and rising, but it is encouraging that the increase in cases still does not appear to be associated with a similar increase in hospitalisations and deaths. This is testament to the continued success of the vaccination programme in reducing the incidence of severe disease.

The best way to keep yourself and those around you safe is to get both doses of the vaccine as soon as you are eligible. However, while vaccines offer excellent protection, they do not completely eliminate risk. As we approach the end of restrictions, it is as important as ever that we continue to exercise caution. Take your free twice-weekly rapid tests and if you have symptoms, you should book a PCR test immediately and stay at home until you receive your result.

Friday 9 July

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

PHE’s weekly COVID-19 variant cases data shows that numbers of the Delta (VOC-21APR-02) variant in the UK have risen by 54,268 since last week to a total of 216,249. This represents a 32% increase. Of these, 44 are the Delta AY.1 sub lineage. The Delta variant currently accounts for approximately 99% of cases that are sequenced across the UK.

PHE has also published an updated variant technical briefing today. It shows that secondary attack rates (the likelihood of an infection occurring in a given context) amongst household contacts of cases with Delta has continued to fall, and is estimated at 10.3% for exposure events in week commencing 7 June 2021. Despite this continued fall, secondary attack rates for both household and non-household contacts of cases with Delta remain higher than for Alpha.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency, said:

The data continues to show that the sharp increase in cases that we are seeing is not being followed by a similar increase in hospitalisation and death. This is because 2 doses of the available vaccines offer a high level of protection against the Delta variant. Getting both jabs is the best way to ensure you and the people you love remain safe, so we once again urge everyone to come forward as soon as they are eligible.

As we approach the planned end of restrictions, we must remain cautious and careful. Cases are rising across the country, and whilst the vaccines offer excellent protection, they do not offer 100% protection. Be sensible, and follow ‘hands, face, space, fresh air’ at all times and make sure to get tested if required.

Friday 2 July

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

PHE’s weekly COVID-19 variant cases data shows that numbers of the Delta (VOC-21APR-02) variant in the UK have risen by 50,824 since last week to a total of 161,981. This represents a 46% increase. Of these, 42 are the Delta AY.1 sub lineage.

The Delta variant currently accounts for approximately 95% of cases that are sequenced across the UK.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency said:

Cases across the UK continue to rise and it is incredibly important that we do not forget to be careful. The best thing we can do to protect ourselves and the people we love is to get the vaccine if eligible, get tested twice a week and practice ‘hands, face, space, fresh air’ at all times.

Although cases are rising, we are not seeing a proportional rise in the number of people who are being admitted to hospital. The data suggest this is testament to the success of the vaccination programme so far and clearly demonstrates the importance of getting both doses of the vaccine. Come forward as soon as you are eligible. It will help us to break the chain of transmission, and it will save lives.

Friday 25 June

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

Delta cases continue to rise across the UK

PHE’s weekly COVID-19 variant cases data shows that numbers of the Delta (VOC-21APR-02) variant in the UK have risen by 35,204 since last week to a total of 111,157. This represents a 46% increase. Of these, 42 are the Delta AY.1 sub lineage. The Delta variant now accounts for approximately 95% of cases that are sequenced across the UK.

PHE has also published the new edition of the variant technical briefingwhich continues to show that the vaccines continue to have a crucial effect on hospitalisation and death.

An additional 514 people were admitted to hospital in England with a diagnosis of COVID-19 in the week up to 21 June. Of these, 304 were unvaccinated.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency said:

Through the success of our vaccination programme, data suggest we have begun to break the link between cases and hospitalisations. This is hugely encouraging news, but we cannot become complacent. Two doses of vaccine are far more effective against COVID-19 than a single dose, so please make sure that you come forward to get your second dose as soon as you are invited.

Whilst vaccines provide excellent protection, they do not provide total protection, so it is still as important as ever that we continue to exercise caution. Protect yourself and the people around you by working from home where possible, and by practising ‘hands, face, space, fresh air’ at all times.

New variant under investigation

A further variant, Lambda (C.37) has been designated as a variant under investigation (VUI) on 23 June due to international expansion and several notable mutations including L452Q and F490S. The World Health Organization (WHO) classified Lambda as a Variant of Interest on 14 June.

Six cases of Lambda have been identified across the country to date, all have been linked to overseas travel. The earliest documented sample was reported in Peru and Lambda has been sequenced in 26 countries to date.

There is currently no evidence that this variant causes more severe disease or renders the vaccines currently deployed any less effective. PHE is carrying out laboratory testing to better understand the impact of mutations on the behaviour of the virus.

All appropriate public health interventions will be undertaken, including additional contact tracing and targeted testing. Where cases have been identified, additional follow-up of cases, testing of contacts and if required targeted case finding will be deployed to limit its spread.

Issue affecting data collection

The Wellcome Sanger Institute is currently investigating an operational issue in the pre-sequencing process which caused potential cross-contamination of a number of positive COVID-19 samples and therefore a delay in retrieving sequencing results. However, these samples were PCRtested before they were transferred to the Sanger Institute meaning all citizens will have received their correct test result and positive cases will have already been contacted and asked to isolate.

As a result of this issue, around 12,000 samples have not been included in the total number published today, so this number of confirmed variants to date is likely to be an underestimate.

PHE scientists, together with experts from the Wellcome Sanger Institute, are reviewing this data to establish to what extent genomic information may be recoverable from those that were sequenced.

As well as whole genome sequencing, a new technology called genotype assays is being used in NHS Test and Trace laboratories to rapidly detect COVID-19 mutations that indicate a variant of concern (VOC). This means there is still VOC data available for health protection teams and other public health professionals, giving them the intelligence they need to monitor the spread of variants.

Friday 18 June

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

Delta variant cases continue to rise

PHE’s weekly COVID-19 variant cases data shows that numbers of the Delta (VOC-21APR-02) variant in the UK have risen by 33,630 since last week to a total of 75,953. The most recent data show 99% of sequenced and genotyped cases across the country are the Delta variant.

Data show an increased risk of hospitalisation with Delta compared to Alpha, although PHE’s analysis shows that 2 doses of vaccine gives a high degree of protection against hospitalisation, estimated to be more than 90%.

According to PHE’s latest variant technical briefing, as of 14 June, a total of 806 people have been hospitalised with the Delta variant, an increase of 423 since last week. Of these, 527 were unvaccinated, and only 84 of the 806 had received both doses.

PHE now publishes the number of deaths among people who have tested positive for Delta within the past 28 days. The case fatality rate remains low for Delta. However, deaths tend to happen some weeks after infection and the majority of cases were confirmed less than 28 days ago. It is therefore too early to judge the case fatality of Delta compared to Alpha or other variants.

Dr Jenny Harries, Chief Executive, UK Health Security Agency said:

Cases are rising rapidly across the country and the Delta variant is now dominant. The increase is primarily in younger age groups, a large proportion of which were unvaccinated but are now being invited to receive the vaccine. It is encouraging to see that hospitalisations and deaths are not rising at the same rate but we will continue to monitor it closely. The vaccination programme and the care that we are all taking to follow the guidance are continuing to save lives.

Please make sure that you come forward to receive both doses of the vaccine as soon as you are eligible. Don’t drop your guard – practise ‘hands, face, space, fresh air’ at all times.

A breakdown of Delta variant cases by lower-tier local authority is available.

Friday 11 June

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

Rapid genotyping test speeds up availability of Delta data as cases continue to rise

Novel genotyping tests are being used to detect the Delta (VOC-21APR-02) variant, giving a result for action within 48 hours. As cases of the variant continue to rise, the tests are helping to rapidly inform public health action.

Data from these tests is available for the first time this week, as PHEfigures shows that cases have risen by 29,892 to 42,323.

The data indicates that over 90% of new COVID-19 cases in the UK are now the Delta variant, which continues to show a significantly higher rate of growth compared to the Alpha variant.

Positive tests identified through genotyping are subsequently confirmed through whole genome sequencing and recent data have shown them to be extremely accurate in indicating a positive variant result. This allows earlier detection of trends and improved public health response. These results have been available to Health Protection Teams for several weeks and are already being used to develop local and national activities. Most recently, the tests allowed for the early identification of rising cases in areas including Greater Manchester and Lancashire, triggering a support package to control the variant in these areas.

New research from PHE suggests that the Delta variant is associated with an approximately 60% increased risk of household transmission compared to the Alpha variant. Growth rates for Delta cases are high across the regions, with regional estimates for doubling time ranging from 4.5 days to 11.5 days

With this variant now accounting for the overwhelming majority of new cases in the UK, it is encouraging to see that the increase in cases is not yet accompanied by a similarly large increase in hospitalisations. PHE will continue to monitor closely over the next few weeks, but the data currently suggest that the vaccination programme continues to mitigate the impact of this variant in populations who have high 2 dose vaccine coverage.

Dr Jenny Harries, Chief Executive of the UK Health Security Agency, said:

With numbers of Delta variant cases on the rise across the country, vaccination is our best defence. If you are eligible, we urge you to come forward and be vaccinated. Remember that 2 doses provide significantly more protection than a single dose.

However, while vaccination reduces the risk of severe disease, it does not eliminate it. With data showing that Delta is significantly more transmissible than Alpha, it is just as important as ever to follow public health advice, which has not changed. Get vaccinated, work from home where you can and remember ‘hands, face, space, fresh air’ at all times. These measures work, and they save lives.

Thursday 3 June

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

Delta (VOC-21APR-02) variant now dominant in the UK

PHE’s weekly coronavirus (COVID-19) variant cases data shows that cases of the Delta (VOC-21APR-02) variant in the UK have risen by 5,472 since last week to 12,431.

Although there is some regional variation, PHE experts now believe that Delta (VOC-21APR-02) has overtaken Alpha (VOC-20DEC-01) as the dominant SARS-CoV-2 variant in the UK.

Early evidence suggests there may be an increased risk of hospitalisation for Delta (VOC-21APR-02) compared to Alpha (VOC-20DEC-02) although more data is needed for us to have more confidence in that finding. This week, 278 people with the Delta (VOC-21APR-02) variant attended A&E, resulting in 94 people being admitted to hospital overnight. Last week, 201 people attended A&E, with 43 admissions. Once again, the majority of these had not been vaccinated.

The most affected areas remain Bolton, where cases have risen by 795 to 2149, and Blackburn with Darwen which has seen 368 new cases, bringing it to 724 in total. There are encouraging signs that the transmission rate in Bolton has begun to fall and that the actions taken by residents and local authority teams have been successful in reducing spread.

Dr Jenny Harries, Chief Executive, UK Health Security Agency, said:

With this variant now dominant across the UK, it remains vital that we all continue to exercise as much caution as possible. The way to tackle variants is to tackle the transmission of COVID-19 as a whole. Work from home where you can, and practise ‘hands, face, space, fresh air’ at all times.

If you are eligible and have not already done so, please come forward to be vaccinated and make sure you get your second jab. It will save lives.

In Bolton, local teams have gone door to door in targeted areas on consecutive weekends to distribute test kits, share vital safety messages and encourage people to get the vaccine at a local drop-in centre. Take up of both testing and the vaccine has been positive.

Blackburn with Darwen has also seen local teams making door-to-door visits, and over 10,000 additional PCR tests have been given out. Mobile testing units have been deployed to the area and wastewater sampling continues, in order to track the spread of the variant.

PHE has also published a breakdown of outbreaks and clusters of variants in schools and other settings.

Outbreaks and clusters in primary and secondary schools are at low levels but we have seen a slight increase over recent weeks, in line with higher levels of the Delta (VOC-21APR-02) variant circulating in the community.

The latest PHE data suggest that there have been 97 confirmed COVID-19 outbreaks in primary and secondary schools that have had at least one variant case linked to them over the most recent 4-week period. This represents around 1 in 250 schools.

PHE’s health protection teams continue to work with local authorities and schools to carry out surveillance of COVID-19 cases in schools to understand and reduce transmission in these settings.

PHE experts continue to urge everybody to remain cautious as the country approaches the next stage of the roadmap. Variant cases are on the increase in several areas and it is absolutely crucial that everyone plays their part in preventing their spread.

Thursday 27 May

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

The dominant variant continues to be VOC-20DEC-01 (B.1.1.7) and PHEwill continue to monitor all variants closely. The best way to stop the spread of the virus is to remember: hands, face, space and follow the restrictions in place.

Public health leaders urge caution in areas of high variant prevalence

PHE’s latest weekly variant cases data shows that cases of VOC-21APR-02 have risen by 3,535 to 6,959 since last week.

The most affected areas continue to be Bolton, Bedford and Blackburn with Darwen, which have seen 1,354, 366 and 361 confirmed cases, respectively. There are small numbers of cases of VOC-21APR-02 in most parts of the country. PHE have published a full breakdown of VOC-21APR-02 cases by lower-tier local authority.

In some affected areas, hospitalisations are rising. Hospital attendances and admissions are predominantly in unvaccinated individuals, highlighting how crucial it is that people in these areas come forward to receive vaccination. Nationwide, up to 25 May, 201 people who were confirmed to have VOC-21APR-02 attended A&E, resulting in 43 admissions. These numbers will be updated with new sequencing results on a weekly basis.

Evidence shows that VOC-21APR-02 is likely to be more transmissible than the dominant B.1.1.7 ‘Kent’ variant. Cases of VOC-21APR-02 have continued to grow faster than B.1.1.7 but an increase in overall cases of coronavirus (COVID-19) infections has only been seen in a small number of areas. PHE experts are monitoring the situation closely to establish how much more transmissible VOC-21APR-02 may be. It is crucial that everybody, particularly in the most affected areas, take particular care to remain responsible and vigilant.

PHE study showed that 2 doses of vaccine offers high levels of protection against symptomatic disease from VOC-21APR-02. We expect the vaccines to be effective at preventing hospitalisation and death, so it is vital to get both doses to gain maximum protection against all existing and emerging variants.

Dr Jenny Harries, Chief Executive, UK Health Security Agency, said:

With cases of the variant first identified in India continuing to rise in some areas, we are urging people to be very cautious and follow the guidance on hygiene, face coverings, social distancing and meeting outdoors. We now know that getting both vaccine doses gives a high degree of protection against this variant and we urge everyone to have the vaccine when the NHS invites you.

Please follow the public health advice and make sure that you remain careful, work from home if you can, meet people outside where possible and remember ‘hands, face, space, fresh air’ at all times. This is the best way to protect yourself and your loved ones from this variant.

In London, PHE is working across the health system and with borough council leaders in parts of the city where cases have been identified. A targeted approach is being used throughout the city, including Hounslow and other parts of west London, where dispersed clusters have been detected. This includes whole genome sequencing, PCR testing, settings-based testing, enhanced contact tracing, self-isolation support, and enhanced vaccine deployment to ensure that second doses for priority groups are brought forward and that maximum uptake is achieved for first doses.

In Bolton, the army working with RE:SILIENT visited over 4,000 houses, delivering over 1,500 test kits. This was in addition to the national surge team efforts, which saw over 9,000 properties visited and over 3,000 kits given out

In Blackburn with Darwen, enhanced vaccine uptake support has resulted in over 82% of registered patients in cohorts 1 to 10 receiving their first dose.

NHS Test and Trace have supplied more than 400,000 additional PCRtest kits to the most affected areas to make sure that everyone who needs a test can get one.

In addition, over 190 existing test sites have been reassigned to provide PCR test kits in areas where VOC-21APR-02 prevalence is high. This means tests can be sequenced faster, so VOC-21APR-02 cases are found sooner.

Over 300 Mobile Testing Units (MTUs) have been deployed to provide PCR test kits for those without symptoms in high-prevalence areas, including to more than 35 schools so students, parents and staff can get a PCR test as quickly as possible.

National marketing support is in place to make sure that local communities are kept well informed about the situation in their area, how and where to get a test, and about any public health interventions, such as surge testing.

New Vvariant under investigation

A further variant, VUI-21MAY-02 (C.36.3), has been designated as a variant under investigation (VUI) on 24 May on the basis of the mutation profile and increased importation from a widening international area.

There have been 109 cases of VUI-21MAY-02 dispersed across the country to date. The C.36.3 variant was first detected in Thailand, in cases who had travelled from Egypt.

There is currently no evidence that this variant causes more severe disease or renders the vaccines currently deployed any less effective. PHE is carrying out laboratory testing to better understand the impact of the mutations on the behaviour of the virus.

All appropriate public health interventions will be undertaken, including additional contact tracing and targeted testing. Where cases have been identified, additional follow-up of cases, testing of contacts and if required targeted case finding will limit its spread.

More information will be available in variant technical briefing 13, which Public Health England will publish on Thursday 27 May.

Thursday 20 May

Further rise in VOC-21APR-02 detected and new VUIdesignated

Public Health England’s (PHE) latest weekly variant cases data shows that cases of VOC-21APR-02 have risen by 2,111 to 3,424 since last week.

Cases are still predominantly affecting the North West of England – particularly Bolton – and London, but we are seeing clusters of cases across the country.

There is evidence that VOC-21APR-02 is growing rapidly and may be more transmissible than VOC-20DEC-01, the ‘Kent variant’ that is currently dominant in the UK. Experts at PHE are monitoring the situation closely.

In London, PHE is working in close partnership across the health system and with borough council leaders in parts of the city where cases have been identified. A targeted approach is being used throughout the city to target London’s many small dispersed clusters. This includes whole genome sequencing, polymerase chain reaction (PCR) testing, settings-based testing, enhanced contact tracing, self-isolation support, and enhanced vaccine deployment to ensure that second doses for priority groups are brought forward and that maximum uptake is achieved for first doses.

In Bolton, more than 33,000 test kits have been given out as part of the surge testing programme, not including tests taken by residents visiting Mobile Testing Units (MTU). Health officials visited more than 9,000 properties during door-to-door visits over the weekend, giving out over 3,400 test kits.

In Blackburn with Darwen and Sefton, targeted local testing is underway in response to the rise in VOC-21APR-02, including mobile and drive-through test centres being set up and pop-up tests sites in specific communities. New vaccination centres have opened to boost the delivery of vaccines and additional supply of first doses has been secured.

In total, more than 180,000 additional PCR test kits have been deployed to affected areas to make sure everyone who needs a test can get one, and over 170 existing test sites in those areas have been switched to provide PCR test kits – this means tests can be sequenced faster so variant cases are found sooner.

Over 150 MTUs have been deployed to provide PCR test kits for those without symptoms in the most affected areas.

NHS Test and Trace has activated marketing to let some local communities know if surge testing is happening in their area and to explain how, when and where to get their tests, and enhanced contact tracing is in place for all positive cases and their contacts in areas affected by VOC-21APR-02 to help identify and break any potential chains of transmission. All confirmed cases have been told to self-isolate and their contacts are being identified.

So far, more than 20,000 positive samples from the most affected areas have been analysed using the new genotype assay method. In parallel, the majority of positive samples undergo genome sequencing for definitive confirmation of the variant cases.

Wastewater monitoring has been increased in affected areas to help identify early warning signals of where variants may be present. Wastewater monitoring can detect the presence of variants in areas where it has not yet been detected through clinical testing. This allows us to notify local decision makers at an early stage so they can take early action to contain the spread of the virus. Where an outbreak has already been detected, wastewater monitoring can provide additional insights into its geographical spread.

Dr Meera Chand, COVID-19 Incident Director at PHE, said:

We are very grateful to those who have turned out in their thousands in Bolton to be vaccinated. As per advice from the Joint Committee on Vaccines and Immunisation (JCVI), we particularly urge anyone who is yet to have their second dose to make sure they come forward and take up the offer as soon as it is due.

This is vitally important in the light of our current assessment that VOC-21APR-02 has grown rapidly in England and may be highly transmissible. PHE will continue to monitor all variants closely, paying particular attention to the impact on hospitalisations and deaths which will help us to understand the protective effects of the vaccine.

The best way to halt the spread of any variant is to test regularly using lateral flow tests or using PCR if you have symptoms, and to isolate if you or someone in your household tests positive or if you have returned from an amber or red list country. You should continue to work from home where possible and remember that the virus is harder to spread outside.

There is currently no evidence to suggest the vaccines will be less effective in protecting people against severe illness and hospitalisation from VOC-21APR-02. It is highly likely that the vaccines offer significant protection against severe disease, hospitalisation and death, which is why it’s vital to get both vaccine doses as soon as you are offered them. Further work is being rapidly carried out to understand more about the protection the vaccines offer, including impact on transmission.

Everyone in the country, and especially those in areas where a Variant of Concern is present in high rates, should take up the offer of twice-weekly testing.

Although some restrictions have eased, PHE continues to urge caution. Follow the public health advice, get your vaccine when offered it, and practise ‘hands, face, space, fresh air’.

Dr Jenny Harries, Chief Executive, UK Health Security Agency, said:

As cases of VOC-21APR-02 continue to rise, it is absolutely vital that people living in areas where prevalence is high come forward to get the vaccine. It is the best defence we have against the spread of this disease.

As we start to get back to normal life, it is very important that we do not become complacent. All of us need to remain responsible and vigilant. Get tested regularly, get the vaccine when offered it, and practise ‘hands, face, space, fresh air’. It will save lives.

New variant under investigation

A further variant, VUI-21MAY-01, has been designated as a variant under investigation (VUI) by PHE.

The variant is from a lineage which was designated a signal in monitoring on 6 May 2021 based on an unusual mutation profile. PHE has been monitoring the variant since April.

There have been 49 cases of VUI-21MAY-01 across the country to date, mainly concentrated in Yorkshire and the Humber.

There is currently no evidence that this variant causes more severe disease or renders the vaccines currently deployed any less effective. PHE is carrying out increased laboratory testing to better understand the impact of the mutations on the behaviour of the virus.

All appropriate public health interventions are being undertaken, including additional contact tracing and targeted testing. Where cases have been identified, additional follow-up of cases, testing of contacts and targeted case finding will limit the spread of variants.

If you have symptoms of COVID-19 you should seek a PCR test as soon as possible. If you are tested positive then you and your household must stay at home and not leave the house for any reason for 10 days.

More information will be available in variant technical briefing 12, which Public Health England will publish on Friday 21 May.

Thursday 13 May

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

The dominant variant continues to be VOC-20DEC-01 (B.1.1.7) and PHEwill continue to monitor all variants closely. The best way to stop the spread of the virus is to remember: hands, face, space and follow the restrictions in place.

Further rise in VOC-21APR-02 cases detected

The latest PHE data show cases of the Variant of Concern, VOC-21APR-02, first detected in India, have risen from 520 to 1,313 cases this week in the UK. The variant was confirmed as a Variant of Concern on 7 May after a rise in cases and evidence of spread in some areas. PHE is actively monitoring the impact of this variant and its severity and is taking all appropriate public health actions to limit the spread.

Cases and clusters are being rapidly investigated to identify close contacts of those who test positive, encourage testing uptake and to ensure that people self-isolate when required. These measures, implemented by PHE health protection teams, NHS Test and Trace and local authorities, are the most effective way of breaking the chains of transmission. Additional control measures, including targeted case finding, will be implemented where there is evidence of increased spread and investigations are underway in specific settings to investigate clusters and outbreaks.

More than 60,000 additional PCR test kits have been distributed so far as part of ongoing surge testing activity for VOC-APR21-02, with cases and close contacts traced and asked to isolate. To find any new cases of the variant, over 150 existing test sites and 10 schools have distributed test kits, with 133 Mobile Testing Units deployed to provide PCR testing for people without symptoms.

Across the North West, significant work is underway with local councils and partners in specific areas where variant cases have been identified. In Bolton mobile testing units have been deployed and door to door PCRtesting has been offered to 22,000 residents. A vaccine bus has been established in the heart of the community to increase vaccine uptake as part of a wider drive.

In London, PHE is working in close partnership across the health system and with borough councils in parts of the city where cases have been identified. PCR testing, whole genome sequencing and enhanced contact tracing are being used throughout the city to target the many small dispersed clusters. Taking this community-led approach has already proved effective in reducing transmission of variants in London to date.

Dr Susan Hopkins, COVID-19 Strategic Response Director at PHE, said:

Cases of this variant are rising in the community and we are continuously monitoring its spread and severity to ensure we take rapid public health action. We need to act collectively and responsibly to ensure that variants do not impact on the progress we have all made to drive down levels of Covid-19 and the increased freedom that brings. That means you should pay attention to and act on the local health advice in your area. Testing and isolating when required not only limits spread, it helps us to better understand how the variant behaves in the community which is vital to taking effective and proportionate action moving forward.

If you’re asked to take a test please do. The way to limit the spread of all variants is the same. Keep your distance, wash your hands regularly and thoroughly, cover your nose and mouth when inside, keep buildings well ventilated and meet people from other households outside.

PHE is asking the public to continue to:

  • work from home where you can
  • follow the current guidance on mixing with others
  • take up the universal, free offer of twice weekly LFDs tests
  • if positive, order a confirmatory PCR test kit and stay at home
  • get vaccinated when you are called to do so

The other variants first detected in India, VUI-21APR-01 and VUI-21APR-03 have not been re-designated as VOCs, but this will be kept under constant review.

Following close monitoring, one variant under investigation VUI-21MAR-01, which includes the spike mutations E484K and N501Y, is now considered provisionally extinct in the UK. Designated a variant under investigation on 4 March, the contacts of confirmed cases were traced and followed public health advice to isolate. PHE defines a variant as provisionally extinct after 12 weeks without detection although we continue to monitor to see if they reappear.

Thursday 7 May

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

The dominant variant continues to be VOC-20DEC-01 (B.1.1.7) and PHEwill continue to monitor all variants closely. The best way to stop the spread of the virus is to remember: hands, face, space and follow the restrictions in place.

VUI-21APR-02 reclassified as a Variant of Concern (VOC)

Following a rise in cases in the UK and evidence of community transmission, PHE has reclassified VUI-21APR-02 (B.1.617.2, classified as a variant under investigation (VUI) on 28 April) as a Variant of Concern (VOC), now known as VOC-21APR-02.

This is based on evidence which suggests this variant, first detected in India, is at least as transmissible as B.1.1.7 (the Kent variant). The other characteristics of this variant are still being investigated.

There is currently insufficient evidence to indicate that any of the variants recently detected in India cause more severe disease or render the vaccines currently deployed any less effective. PHE is carrying out laboratory testing, in collaboration with academic and international partners to better understand the impact of the mutations on the behaviour of the virus.

Cases of VOC-21APR-02 have increased to 520 from 202 over the last week and almost half the cases are related to travel or contact with a traveller. The cases are spread across the country, however, the majority of the cases are in 2 areas – the North West (predominantly Bolton) and London – and this is where we are seeing the greatest transmission.

PHE health protection teams are working with local authorities, Directors of Public Health (DsPH) and NHS Test and Trace to detect cases and limit onward spread.

Surge and community testing is an effective way of finding and isolating new cases of variants and will be deployed where there is evidence of community transmission. This is in addition to the comprehensive work that is already underway to trace and test all contacts of cases.

Everyone in the affected areas will be asked to get a test, even if they don’t have symptoms. If someone tests positive, they must isolate to stop the spread.

In partnership with local DsPH, additional measures are being implemented across the country where there are clusters, to contain the spread. These include:

  • enhanced contact tracing for those testing positive with a VOC to define locations they may have acquired or transmitted infection to focus further testing
  • enhanced community and surge testing in areas defined by the local authorities and regional teams
  • working closely with communities and community leaders to ensure that individuals have the right support to test and isolate
  • increased community engagement, including ensuring that messages are accessible in languages that are used by communities and provided by trusted community representatives

Where clusters of other VOCs are detected, PHE will continue to take all appropriate public heath action to break the chains of transmission.

Understanding how this virus behaves in the community is key to assessing its transmissibility, severity and whether it responds to the vaccines currently in use, all of which help to determine the risk to the public from this variant. While overall rates of COVID-19 remain low, there are actions that everyone can take to reduce spread.

PHE is encouraging the public to continue to:

  • work from home where you can
  • follow the current guidance on mixing with others
  • take up the universal, free offer of twice weekly LFDs tests
  • if positive, order a confirmatory PCR test kit and stay at home
  • get vaccinated when you are called to do so

Dr Susan Hopkins, COVID-19 Strategic Response Director at PHE, said:

The way to limit the spread of all variants is the same and although we are all enjoying slightly more freedom, the virus is still with us. Keep your distance, wash your hands regularly and thoroughly, cover your nose and mouth when inside and keep buildings well ventilated and meet people from other households outside. If you are told to get a test, if you have any symptoms at all or have been in contact with someone who has tested positive, please make sure you get tested too.

We are monitoring all of these variants extremely closely and have taken the decision to classify this as a Variant of Concern because the indications are that this VOC-21APR-02 is a more transmissible variant.

The current evidence suggests that the other variants detected in India, VUI-21APR-01 and VUI-21APR-03 are not VOCs, but this will be kept under constant review and investigations are ongoing into the reasons behind the different behaviours of these variants.

Previous

Thursday 29 April

Public Health England (PHE) releases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK.

The dominant variant continues to be VOC-20DEC-01 (B.1.1.7) and PHEwill continue to monitor all variants closely. The best way to stop the spread of the virus is to remember: hands, face, space and follow the restrictions in place.

Two VUIs added to B.1.617 group

Two variants have been designated Variants Under Investigation by PHE.

The 2 variants, VUI-21APR-02 and VUI-21APR-03, share the same parent lineage (B.1.617) as VUI-21APR-01, first identified in India. PHE has been monitoring these variants since early April.

VUI-21APR-01 was designated a variant under investigation in April. The variant is from the B.1.617 lineage – a distinct fingerprint of genetic mutations. We have also identified cases of 2 additional variants, which are part of the same lineage and so are genetically similar.

While closely related, their genetic profiles are different and have been designated as separate Variants Under Investigation so that we can track them properly and take fast public health action as needed.

VUI-21APR-02 does not have the mutation E484Q while VUI-21APR-03 shares the L452R and E484Q mutations found in VUI-21-APR-01.

There is currently no evidence that these variants cause more severe disease or render the vaccines currently deployed any less effective. PHEis carrying out increased laboratory testing, in collaboration with international partners to better understand the impact of the mutations on the behaviour of the virus and to ensure all appropriate public health interventions are taken.

Identified case numbers remain low and are geographically dispersed in England. Where cases have been identified, additional follow up of cases, testing of contacts and targeted case finding will be used to limit the spread of these variants.

PHE has identified:

  • 172 cases of VUI-21APR-01
  • 202 cases of VUI-21APR-02
  • 5 cases of VUI-21APR-03

All appropriate public health interventions will be undertaken, including additional contact tracing and targeted testing.

Thursday 15 April

New variant under investigation (VUI) designated

A new variant has been designated a variant under investigation (VUI) by PHE.

The variant, first detected in India, includes a number of mutations including E484Q, L452R, and P681R.

PHE has identified 77 cases of this variant in the UK and all appropriate public health interventions will be undertaken, including enhanced contact tracing.

This variant has been designated VUI-21APR-01. PHE and international partners continue to monitor the situation closely.

Tuesday 16 March

Two additional cases of Variant of Concern VOC-21JAN-02 (P.1) found in England

Two more cases of the Variant of Concern VOC-21JAN-02 (P.1) have been identified in England – one in the West Midlands and one in Haringey, London.

Both cases are linked with international travel to Brazil. The case in the West Midlands was identified following their arrival at Birmingham Airport, where they were tested and quarantined as part of the managed hotel quarantine process.

The London case was picked up through surge testing. Surge testing will be stepped up in the affected area, and contact tracing teams have undertaken a comprehensive investigation to identify any further contacts.

The latest cases bring the total number of P.1 variant cases in the UK to 12 – 9 in England and 3 in Scotland, all of which have links to travel or to a previously confirmed case that has travelled to Brazil.

New variant under investigation (VUI) designated

A new variant has been designated a variant under investigation (VUI) by Public Health England (PHE).

On 9 March, PHE noted a report of 33 cases of a new variant reported by the Philippines. The variant includes a number of notable mutations including E484K and N501Y, which are found in several other variants of concern.

PHE has identified 2 cases of this variant in England. One of the cases is linked with international travel and the other is currently under investigation. All appropriate public health interventions are being undertaken.

This variant has been designated VUI-21MAR-02 (P.3). PHE and international partners continue to monitor the situation closely.

Saturday 13 March

Four more cases of Variant of Concern VOC-202101/02 (P.1) found in England

Four more cases of the Variant of Concern VOC-202101/02, also known as P.1, have been identified in England – 3 in South Gloucestershire and one in Bradford, West Yorkshire.

The cases in South Gloucestershire are all close or household contacts of the 2 existing P.1 cases in the area. They were offered testing in response to the initial cases.

Specialist contact tracing teams have undertaken a comprehensive investigation to identify any further contacts and additional testing has been in place since the initial cases were identified.

The individual in Bradford tested positive for coronavirus (COVID-19) in late February after travelling back from Brazil via Paris on 14 February 2021. Subsequent genomic sequencing confirmed the case as the P.1 variant. Contact tracing teams have followed up close contacts of the individual and advised them to isolate and get a test.

The latest cases bring the total number of P.1 variant cases in the UK to 10 – 7 in England and 3 in Scotland, all of which have links to travel or to a previously confirmed case that has travelled to Brazil.

New variant under investigation (VUI) designated in UK

A new variant identified in the UK has been designated a variant under investigation (VUI) by PHE.

VUI-202103/01 (lineage B.1.324.1) was designated a VUI on 4 March after 2 cases were found in the South East of England in individuals who had recently travelled to Antigua. Despite the travel history of these cases there is no scientific evidence to determine where this variant first emerged.

The variant contains the spike mutations E484K and N501Y, both usually associated with variants of concern (VOC), however it does not feature specific deletions that would lead to a designation as a VOC.

Contact tracing teams have completed thorough investigations to identify and follow up any close contacts and no additional cases have been found to date.

Friday 5 March

Contact tracers successfully identify sixth case of P.1 Variant of Concern

PHE and NHS Test and Trace teams have successfully located the third individual in England who tested positive for the P.1 Variant of Concern that originated in Manaus, Brazil.

Tracing teams narrowed their search to a small number of households in Croydon, South London, when an individual from the borough made themselves known by responding to calls made by specialist contact tracers.

NHS Test and Trace were then able to match the barcode from the individual’s testing pack to the variant test result.

PHE is now carrying out enhanced contact tracing with the individual and other members of their household. The case had been in contact with an individual who travelled from Brazil in early February.

Although investigations are ongoing, current early indications are that all members of the household isolated for the correct amount of time after the traveller returned and after the case developed symptoms.

Doctor Fu-Meng Khaw, Strategic Response Director for PHE and Deputy Chief Medical Adviser for Test and Trace, said:

The identification of this individual is the result of an enormous collaborative effort between specialist teams at NHS Test and Trace and Public Health England.

Staff have been working around the clock to pursue every line of investigation and this is a fantastic result that enables us to fully investigate the circumstances around the case and reduce the risk of onward transmission.

As an additional precaution, we’re working closely with Croydon Council to put in place further testing in the area.

We are continuing to monitor all variants closely and the best way to protect against all COVID-19 infections is to remember the basics of Hands, Face, Space.

Thursday 4 March

New variant under investigation designated in the UK

Sixteen cases of a new variant, VUI-202102/04 (lineage B.1.1.318), have been identified in the UK. The variant has been designated a variant under investigation (VUI) by Public Health England (PHE).

Cases of this variant, understood to have originated in the UK, were first identified on 15 February through genomic horizon scanning. All individuals who tested positive and their contacts have been traced and advised to isolate.

Following assessments, the variant was designated a VUI on 24 February. It contains the E484K mutation, which is also found in 2 existing VUIspresent in the UK, but does not feature the N501Y mutation, present in all variants of concern (VOCs).

The addition of this variant as a VUI means there are now a total of 4 VUIsand 4 VOCs currently being tracked in the UK.

Cases with no travel links

As of 3 March:

  • a total of 59 cases of the variant VOC-202012/02, first detected in South Africa, have been found in England where no travel links could be established
  • a total of 26 cases of the variant VUI-202101/01, the P2 variant first detected in Brazil, have been found in England where no travel links could be established

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Tuesday 28 February

Cases of Variant of Concern first detected in Manaus identified in the UK

Up to 6 cases of the Variant of Concern first identified in Manaus, Brazil (P.1) have been detected in the UK. Public Health England (PHE) has identified 3 of these cases of the Variant of Concern in England.

Two of the cases in England are from one household in South Gloucestershire with a history of travel to Brazil and there is a third, currently unlinked case.

The cases in South Gloucestershire were rapidly followed up by the PHEHealth Protection Team – cases and their contacts have been identified and retested. One case that had travelled to Brazil has been isolating at home with their household since returning to the UK.

PHE and NHS Test and Trace are following up with all passengers on Swiss Air flight LX318 travelling from Sao Paulo via Zurich and landing in London Heathrow on 10 February, to provide public health advice and test them and their households. Anyone who returned to the UK at that time should have gone home immediately from the airport and isolated for 10 days.

If you were a passenger on the flight and have not been contacted, please call 01174 503 174 to arrange a test for you and your household contacts.

Although the risk to the wider community is considered low, as a precaution, PHE, working in collaboration with South Gloucestershire Council and NHS Test and Trace, is taking swift and decisive action to deploy surge asymptomatic testing as well as increasing sequencing of positive samples from the area. Residents of South Gloucestershire should visit the council’s website for more information on testing. The most important actions are identifying cases and their contacts and supporting these individuals to isolate effectively.

Further investigation is underway regarding the third case in England. The individual did not complete their test registration card so follow-up details are not available. We are therefore asking for anyone who undertook a test on 12 or 13 February and hasn’t received their result or has an uncompleted test registration card, to call 119 in England or 0300 303 2713 in Scotland for assistance as soon as possible.

The P.1 variant has been designated ‘of concern’ as it shares some important mutations with the variant first identified in South Africa (B.1.351), such as E484K and N501Y.  It is possible that this variant may respond less well to current vaccines, but more work is needed to understand this.

Dr Susan Hopkins, PHE strategic response director for COVID-19 and NHS Test and Trace Medical Advisor, said:

We have identified these cases thanks to the UK’s advanced sequencing capabilities which means we are finding more variants and mutations than many other countries and are therefore able to take action quickly.

The important thing to remember is that COVID-19, no matter what variant it is, spreads in the same way. That means the measures to stop it spreading do not change. Stay at home and if you do need to go out for essential reasons, cover your nose and mouth, wash your hands thoroughly and keep your distance.

We ask that individuals come forward for testing through the symptomatic and asymptomatic test sites across the countries in order to continue to drive down cases in the community.

Background

Three cases of the variant have also been identified in Scotland but these are not linked to these 3 cases in England.

Tuesday 16 February

Public Health England (PHE) has identified 38 cases of COVID-19 which genomic sequencing has shown to feature a specific set of mutations which are currently being referred to as lineage B.1.525. The set of mutations includes the E484K spike protein mutation, which is present on a number of other variants of concern and variants under investigation.

This variant has been designated a variant under investigation (VUI) and will be referred to as VUI202102/03.

The variant has been detected in other countries, including Nigeria, Denmark and Canada.

Cases are geographically dispersed across England. Enhanced contact tracing and genomic sequencing is underway to monitor the situation as it develops.

Professor Yvonne Doyle, Medical Director at PHE, said:

PHE is monitoring data about emerging variants very closely and where necessary public health interventions are being undertaken, such as extra testing and enhanced contact tracing.

There is currently no evidence that this set of mutations causes more severe illness or increased transmissibility.

The best way to stop the spread of the virus is to follow the public health advice: wash your hands, wear a face covering and keep your distance from others. While in lockdown, it is important that people stay at home, where possible.

Regular updates of confirmed variant cases will be provided on this page.

Friday 15 January

As of Thursday 14 January 2021, 35 genomically confirmed and 12 genomically probable cases of the SARS-CoV-2 variant which originated in South Africa (called VOC202012/02 in the UK, also named B1.351 and 501Y.V2 internationally) have been identified in the UK.

Two variants of interest have also been identified in Brazil. The first variant is variant under investigation (VUI) 202101/01 – this variant has a small number of mutations. The spread and significance of this variant remains under investigation. In partnership with COG-UK, 8 genomically confirmed cases of this variant have now been identified in the UK. All necessary public health action is being taken to follow-up the cases.

The second variant has been designated a Variant of Concern by NERVTAG, now termed VOC202101/02, and this variant has more mutations. We have NOT detected this second Brazil originated strain in the UK– this has been detected in Manaus and travellers arriving in Japan.

Laboratory work has begun on the VOC 202012/02 in the UK and is routinely undertaken on all variants under investigation or of concern once samples are available.

Dr Susan Hopkins, COVID Strategic Response Director at Public Health England, said:

We are continuing efforts to understand the effect of the variants on transmissibility, severe disease, mortality, antibody response and vaccine efficacy.

For now, our advice remains the same following detection of a Brazilian variant in the UK, even though this is not the variant detected in Manaus with more mutations: the best way to stop the spread of the virus is to wash your hands, wear a face covering and keep your distance from others. Whilst in lockdown, it is important that we also stay at home unless it is absolutely essential to go out.

Through COG-UK, the UK is a global leader in SARS-CoV-2 genomics, providing around 48% of the genomic data supplied to GISAID, the scientific initiative which allows global, real-time surveillance of the COVID-19 pandemic.

WGS is vital to the global response to the pandemic, allowing us to monitor and understand the evolution of new COVID-19 variants and respond with timely public health interventions.

In addition to the travel ban imposed on South Africa on 23 December 2020, the Department for Transport (DfT) has announced new restrictions for everyone arriving into the country from Namibia, Zimbabwe, Botswana, Eswatini, Zambia, Malawi, Lesotho, Mozambique, Angola, Mauritius and Seychelles.

The restrictions follow new data on the steep rise in incidence of the B1.351 variant, which has vastly increased the risk of community transmission between these 9 southern African countries, as well as the Seychelles and Mauritius which have strong travel links with South Africa.

From 15 January 2021, the DfT has also imposed a subsequent travel ban to the UK from several South American countries and countries with strong travel links to Brazil. Passengers who have been in or transited through Argentina, Brazil, Bolivia, Chile, Cape Verde, Colombia, Ecuador, French Guiana, Guyana, Paraguay, Panama, Portugal (including Madeira and the Azores), Peru, Suriname, Uruguay and Venezuela in the last 10 days will no longer be granted access to the UK.

British and Irish Nationals (and or third country nationals with residence rights in the UK) who have travelled from or transited through these countries must self-isolate for 10 days, as must members of their household. Contact tracing and testing of close contacts of confirmed cases will be used to identify and manage potential transmission. The decision to impose these restrictions has been taken to prevent the spread of the variant of coronavirus, known as VOC202101/02, into the UK.

The Isolation Assurance Service (IAS) will be contacting all returnees from all southern African countries, Mauritius and Seychelles to reinforce the advice to self-isolate, to encourage testing even if asymptomatic and to inform anyone treating/testing them of their recent travel.

Wednesday 23 December

The 2 cases were identified in the UK on 22 December 2020 and both have been in contact with someone who has travelled from South Africa. PHE’s Health Protection Teams have followed up with both cases and contact tracing is underway.

The new variant named B1.351 (also referred to as 501Y.V2) was first detected in Nelson Mandela Bay, South Africa, in samples at the beginning of October. Molecular dating suggests that it could have been in circulation from the end of August.

The rapid spread of the variant in South Africa could be an indication of increased transmissibility but this is not yet confirmed. PHE is investigating this variant and will share its findings in due course. There is currently no evidence to suggest that the variant has any impact on disease severity, antibody response or vaccine efficacy. Epidemiological and virological investigations are also ongoing in South Africa.

It is not uncommon for viruses to undergo mutations; seasonal influenza mutates every year. More than 4,000 variants of SARS-CoV-2 have been identified in the UK and variants have been observed in many other countries.

Dr Susan Hopkins, Chief Medical Adviser on COVID-19 to PHE & Test and Trace, said:

We are investigating this new variant of SARS-CoV-2 which originated in South Africa. Viruses often evolve and this is not unusual. We are carrying out work as a priority to understand the potential risk this variant may cause. It is important to say that there is currently no evidence that this variant causes more severe illness, or that the regulated vaccine would not protect against it.

The best way to stop infection is to stick to the rules – wash our hands, wear a face covering and keep our distance from others.

The recommended control measures to limit the spread of the new variant continue to be testing, following the existing public health guidance and abiding by the restrictions, including ‘Hands, Face, Space’ and limiting your number of contacts. DfT have announced new restrictions for everyone arriving in the country from South Africa.

#AceHealthDesk report …….Published: Sept.18: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here:  https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#delta, #health, #london, #phe, #variants

(LONDON) Press Release MHRA Statement Report: On #COVID19 booster vaccines for Winter 2021 – 2022 #AceHealthDesk report

#AceHealthReport – Sept.15: We are committed to getting safe and effective COVID-19 vaccines to the UK public. This means ensuring that existing COVID-19 vaccines can continue to be used in the most effective way possible…..

#CoronavirusNewsDesk reports on Regulatory updates by the MHRA today on the #COVID19 booster vaccine programme for winter 2021 to 2022…..

Dr June Raine, MHRA Chief Executive said:

We confirmed on 9 September 2021 that the COVID-19 vaccines made by Pfizer and AstraZeneca can be used as safe and effective booster doses. This is an important regulatory change as it gives further options for the vaccination deployment programme which has saved tens of thousands of lives.

The regulatory decision followed a careful review of available data on safety and effectiveness of booster or supplementary vaccine doses by the MHRA and the independent Commission on Human Medicines(CHM, which advises the government.

We have also now looked at data for the Moderna vaccine to be used as a booster, and this has also been reviewed by the CHM experts who concluded that the Moderna vaccine can be used as a safe and effective booster dose, including in a half dose, which also gives an effective boost to antibodies.

The CHM took into account data on waning vaccine effectiveness after the second dose, providing important insights into potentially waning immunity.

The data reviewed showed that giving the booster jabs with flu vaccines at the same time is safe and does not affect an individual’s immune response to either vaccine. Therefore COVID-19 booster doses may be given at the same time as flu vaccines.

We have in place a comprehensive safety surveillance strategy for monitoring the safety of all COVID-19 vaccines and this surveillance includes booster jabs.

As with first and second doses, if anyone has a suspected side effect, please report it to us using our Yellow Card scheme.

#AceHealthDesk report ……Published: Sept.15: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#health, #london, #mhra, #vaccine

(LONDON) Press Release Statement Report: PM Boris Johnson Announces governments plan to manage #COVID19 through Autumn & Winter #AceHealthDesk report

#AceHealthReport – Sept.15: Thanks to the phenomenal success of the vaccination programme, the data continues to show the link between cases, hospitalisations and deaths has weakened significantly…..

#CoronavirusNewsDesk reports that GOVUK Prime Minister has set out the autumn and winter #COVID19 plan with emphasis also on a Plan B should cases overwhelm the NHS

  • Boosters, testing and refreshed public health advice will help keep the virus under control in the coming months
  • Plan B prepared to protect NHS if necessary
  • PM continues to warn the pandemic is not over and public need to remain vigilant

The Prime Minister has today set out the government’s plan to manage Covid throughout autumn and winter.

In England, the number of hospital admissions with Covid has remained relatively stable over the last month.

And although deaths increased at the beginning of the summer, they have remained far below the levels in either of the previous waves.

Over autumn and winter, the government will aim to sustain this progress through:

  • Building our defences through pharmaceutical interventions
  • Identifying and isolating positive cases to limit transmission
  • Supporting the NHS and social care
  • Advising people on how to protect themselves and others
  • Pursuing an international approach

Vaccines will continue to be our first line of defence. All those who were vaccinated during Phase 1 of the vaccine programme (priority groups 1 to 9) will be offered booster jabs from this month – to boost immunity amongst the most vulnerable groups during winter.

The Test, Trace and Isolate programme will continue its important work, with symptomatic PCR testing continuing throughout the autumn and winter.

Lateral flow tests will also remain free of charge but at a later stage, as our response to the virus changes, this will end and individuals and businesses will be expected to bear the cost. The government will engage widely on this before any changes are made.

The legal obligation to self-isolate for those who have tested positive and their unvaccinated contacts will continue, and the financial support payment for those self-isolating on certain benefits will continue in its current format until the end of March.

Our NHS will continue to get the support it needs, with an extra £5.4 billion recently announced for the next 6 months alone for the Covid response.

The public will be offered continued guidance on how to protect themselves and each other – including letting fresh air in, wearing a face covering in crowded and enclosed place where you come into contact with people you don’t normally meet, getting testing and self-isolating if required.

Our tough border policy will remain in place and genomic sequencing capability will be increased to help scientists update our vaccines to defeat new variants.

As the PM also set out, autumn and winter could pose renewed challenges and it is difficult to predict the path of the virus with certainty.

So as the public would expect, there will be a range of ‘Plan B’ measures kept under review to help control transmission of the virus while minimising economic and social damage.

Plan B would include:

  • Introducing mandatory vaccine only Covid status certification in certain, riskier settings.
  • Legally mandating face coverings in certain settings, such as public transport and shops.
  • Communicating clearly and urgently to the public if the risk level increases.

The government could also consider asking people to work from home again if necessary, but a final decision on this would be made at the time, dependent on the latest data – recognising the extra disruption this causes to individuals and businesses.

Ministers would only decide to implement these measures if necessary, and if a range of metrics and indicators mean the NHS is at risk of becoming overwhelmed.

Plan B recognises the success of our vaccination programme – meaning smaller interventions which are far less disruptive can have a much bigger impact on reducing the spread.

The Prime Minister committed to taking whatever action is necessary to protect the NHS, but stressed his belief that the combined efforts of the public and the vaccination programme mean we can avoid plan B and protect our freedoms in the coming months.

#AceHealthDesk report …….Published: Sept.15: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#covi, #govuk, #health, #london

(VIETNAM) #Coronavirus Report: In rapid tests, some 290 of the 306 students and staff on the campus in the city’s urban District 2 tested positive for #COVID19 …Authorities immediately clamped a quarantine on the campus and sent in a small medical team #AceHealthDesk report

#AceHealthReport – Sept.07: When several students at the Evangelical Church of Vietnam South’s (ECVN-S) Institute of Bible and Theology in Ho Chi Minh City developed coughs and fevers on July 20, church authorities immediately called the government health department.

#CoronavirusNewsDesk says according to the Morning Star News Mixed Messages in Vietnam amid #COVID19 Following prior anti-church hype, communist government reacts responsibly to outbreak at Bible school……

In rapid tests, some 290 of the 306 students and staff on the campus in the city’s urban District 2 tested positive for COVID-19. Authorities immediately clamped a quarantine on the campus and sent in a small medical team.

Among the 15 cases that required off-campus hospitalization were those of the dean of students, pastor Nguyen An Thai, and his wife. All the hospitalized were improving except for three students who remained seriously ill at this writing. Many of the infected who remained on campus had coughs and fevers and were weak. A male student on campus who was mildly ill died from a serious fall.

Two Christian doctors and five volunteers of a Christian student fellowship have courageously gone into the quarantined campus to serve for the duration.

Among the first hotspots in what Vietnam calls its fourth wave of COVID-19 was a serious outbreak related to the Revival Ekklesia Mission (REM) house church at the end of April. At that time the government and state-controlled media came down very hard on the small church and its leaders, blaming and shaming them and launching a criminal investigation for spreading a dangerous disease.

Media and public opprobrium began to abate only when Ho Chi Minh City was overcome by other, larger outbreaks in factories and schools.

With the memory of harsh treatment of the REM church outbreak still fresh, however, ECVN(S) leaders appealed to communist authorities to refrain from making a big fuss about the Bible school outbreak in the media, and they complied. Government-church cooperation in this case has been better managed by both sides.

Churches, other Christian organizations and individuals generously donated equipment and supplies to the affected school. The ECVN(S)’s Social and Medical Committee (SOMEDCO), for its part, went into high gear with both local and international support. Churches in Hong Kong donated 100 ventilators. SOMEDCO supplied 10 to their affected school and 20 to the National University in Ho Chi Minh City. Others are being distributed as needed.

The SOMEDCO also prepared care packages worth about $25 each for hundreds of affected and quarantined families, both church members and not, as well as hundreds more for minimally paid public COVID-19 sanitation workers and their families. With food preparation on the campus not possible, SOMEDCO was also tasked with supplying 1,100 meals a day for the quarantined, so far costing about $60,000.

On 21 July SOMEDCO representatives went to the offices of the Vietnam Fatherland Front to present a gift of 1.1 billion Vietnamese dong (US$48,000) for the national fund for purchasing COVID-19 vaccines.

Authorities have approached representatives of the various religions for volunteers to work in COVID-19 hospital wards. The Vietnam Evangelical Alliance of house churches recruited 10 such volunteers. This service requires a three-month commitment, two months of service isolated within the institution and three weeks of quarantine after the service. Catholic news service Asianews reported that teams from various religions supplied 299 such volunteers in Ho Chi Minh City.

Until this “fourth wave,” Vietnam had been among the top 10 countries in the world in controlling the virus. In a country of just under 100 million people, the total numbers of cases at this writing was only 110,000, and deaths were 524. But now Vietnam is recording about 6,000 new infections a day, mostly in Ho Chi Minh City.

In contrast to implementing anti-religion communist ideology, Vietnam seems to be recognizing that religion is not a parasitic leech on society but a willing contributor to the national fight against the pandemic.

Nevertheless, the earlier REM church outbreak appears to have left lingering negative fallout. Many partially registered and non-registered churches that make up at least a third of Vietnam’s evangelicals are experiencing increased scrutiny under the onerous terms of the 2018 Law on Belief and Religion. At least one group has been ordered to cease its online worship services.

Church leaders who do not wish to be quoted by name fear that this scrutiny will lead to more intense government interference and control of their internal affairs.

© 2021 Morning Star News. Articles/photos may be reprinted with credit to Morning Star News. https://morningstarnews.org

#AceHealthDesk report ……Published: Sept.07: 2021:

Editor says …Sterling Publishing & Media Service Agency is not responsible for the content of external site or from any reports, posts or links, and can also be found here on Telegram: https://t.me/acenewsdaily all of our posts fromTwitter can be found here: https://acetwitternews.wordpress.com/ and all wordpress and live posts and links here: https://acenewsroom.wordpress.com/and thanks for following as always appreciate every like, reblog or retweet and free help and guidance tips on your PC software or need help & guidance from our experts AcePCHelp.WordPress.Com

#health, #vietnam